Evidence map›Paper›PMID 23221331›Full record

ArticleRheumatology (Oxford, England)2013

Prevalence and treatment patterns of psoriatic arthritis in the UK.

Alexis Ogdie, Sinéad Langan, Thorvardur Love, Kevin Haynes, Daniel Shin, Nicole Seminara, Nehal N Mehta, Andrea Troxel, Hyon Choi, Joel M Gelfand

Open access · bronzeAbstract read
In one paragraph

Article in Rheumatology (Oxford, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 2 syntheses or guidelines pooled it, 145 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Review
  6. Article
  7. Article
  8. Global epidemiology of spondyloarthritis.Nature reviews. Rheumatology · 2025
    Review
  9. Observational
  10. Review
  11. Observational
  12. Review
  13. Review
  14. Late-onset psoriatic arthritis: data from a nationwide cross-sectional study.Therapeutic advances in musculoskeletal disease · 2025
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article

17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Alexis OgdieDivision of Rheumatology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, 8 Penn Tower, 1 Convention Ave, Philadelphia, PA 19104, USA. alexis.ogdie@uphs.upenn.edu
Sinéad Langan
Thorvardur Love
Kevin Haynes
Daniel Shin
Nicole Seminara
Nehal N Mehta
Andrea Troxel
Hyon Choi
Joel M Gelfand
University of Pennsylvania · US

Funding

Penn Dermatology Research Training ProgramT32AR007465 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI Elizabeth Anne Grice, David Joel Margolis · 1986 to 2026
$9.0M
Clinical Pharmacoepidemiology Training ProgramT32GM075766 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI Sean Hennessy, Charles Edward Leonard · 2006 to 2026
$8.4M
The Risk of Myocardial Infarction in Patients with PsoriasisR01HL089744 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI GELFAND, JOEL M · 2009 to 2013
$3.8M
Psoriasis and the Risk of DiabetesK24AR064310 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI GELFAND, JOEL M · 2013 to 2017
$870k
Human translational studies of CXCL12: a novel GWAS atherosclerosis locusK23HL097151 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI MEHTA, NEHAL N · 2009 to 2011
$411k
Department of Health NIHR/CS/010/014NHLBI NIH HHS K23 HL097151NHLBI NIH HHS R01 HL089744NHLBI NIH HHS R01-HL089744NIAMS NIH HHS K24 AR064310NIAMS NIH HHS T32 AR007465NIGMS NIH HHS T32 GM075766
6 · The paper itself

Abstract

objectivesThe objectives of this study were to determine the prevalence of PsA in The Health Improvement Network (THIN), a large population-based medical records database in the UK, to examine factors associated with prevalent PsA among patients with psoriasis and to describe the use of DMARDs in patients with PsA.

methodsTwo cohorts were derived from THIN to examine the prevalence of PsA in a cross-sectional study among all patients aged 18-90 years and among a subcohort of 4900 psoriasis patients aged 45-65 years. Prescription codes were used to describe therapies after the diagnosis of PsA. Associations for prevalent PsA among psoriasis patients were assessed using logistic regression analysis.

resultsAmong 4.8 million patients in THIN between the ages of 18 and 90 years, 9045 patients had at least one medical code for PsA, giving an overall prevalence of 0.19% (95% CI 0.19%, 0.19%). Of those patients, 45.9% with PsA have been prescribed DMARDs. Among the 4064 confirmed psoriasis patients, the prevalence of PsA was 8.6% (95% CI 7.7%, 9.5%). PsA was more prevalent among patients with severe psoriasis [odds ratio (OR) 3.34; 95% CI 2.40, 4.65], obesity (OR 1.77; 95% CI 1.30, 2.41) and duration of psoriasis for ≥10 years (OR 7.42; 95% CI 3.86, 14.25) in the fully adjusted model.

conclusionThe prevalence of PsA in THIN is consistent with previous population-based estimates. Limitations include a definition of PsA based on a diagnostic code rather than Classification Criteria for Psoriatic Arthritis (CASPAR) criteria. Given the large population of PsA patients, THIN is an important resource for the study of PsA.

Indexed as

AdolescentAdultAgedAged, 80 and overAge DistributionAntirheumatic AgentsArthritis, PsoriaticCohort StudiesCross-Sectional StudiesDatabases, FactualElectronic Health RecordsFemaleHumansMaleMiddle AgedPrevalenceAntirheumatic Agents

Identifiers

PMID23221331
PMCPMC3573270
OpenAlexW2157118376

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.