Evidence map›Paper›PMID 23220574›Full record

ArticleBioinformatics (Oxford, England)2013

Nestly--a framework for running software with nested parameter choices and aggregating results.

Connor O McCoy, Aaron Gallagher, Noah G Hoffman, Frederick A Matsen

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Connor O McCoyProgram in Computational Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA. cmccoy@fhcrc.org
Aaron Gallagher
Noah G Hoffman
Frederick A Matsen

Funding

EARLY INFECTION IN WOMEN EXPOSED MUCOSALLY TO HIV-1R37AI038518 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI OVERBAUGH, JULIE M. · 1999 to 2019
$12.9M
Novel Computational Tools for Studying the Human MicrobiomeR01HG005966 · NHGRI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI FREDRICKS, DAVID NEAL, MATSEN, FREDERICK ALBERT · 2010 to 2012
$1.5M
EARLY INFECTION IN WOMEN EXPOSED MUCOSALLY TO HIV-1R01AI038518 · NIAID · UNIVERSITY OF WASHINGTON · PI OVERBAUGH, JULIE M · 1995 to 1998
–
NHGRI NIH HHS R01 HG005966NHGRI NIH HHS R01 HG005966-01NIAID NIH HHS R01 AI038518NIAID NIH HHS R37 AI038518
6 · The paper itself

Abstract

unlabelledThe execution of a software application or pipeline using various combinations of parameters and inputs is a common task in bioinformatics. In the absence of a specialized tool to organize, streamline and formalize this process, scientists must write frequently complex scripts to perform these tasks. We present nestly, a Python package to facilitate running tools with nested combinations of parameters and inputs. nestly provides three components. First, a module to build nested directory structures corresponding to choices of parameters. Second, the nestrun script to run a given command using each set of parameter choices. Third, the nestagg script to aggregate results of the individual runs into a CSV file, as well as support for more complex aggregation. We also include a module for easily specifying nested dependencies for the SCons build tool, enabling incremental builds. AVAILABILITY: Source, documentation and tutorial examples are available at http://github.com/fhcrc/nestly. nestly can be installed from the Python Package Index via pip; it is open source (MIT license).

Indexed as

SoftwareAlgorithmsComputational BiologyHumans

Identifiers

PMID23220574
PMCPMC3562064

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.