Evidence map›Paper›PMID 23220476›Full record

ReviewAmerican journal of physiology. Regulatory, integrative and comparative physiology2013

Comparative approaches to the study of physiology: Drosophila as a physiological tool.

Wendi S Neckameyer, Kathryn J Argue

Abstract readReview
In one paragraph

Review in American journal of physiology. Regulatory, integrative and comparative physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. A Landscape ofBiology · 2026
    Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Sex and basic science. A Title IX position.American journal of physiology. Regulatory, integrative and comparative physiology · 2014
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Wendi S NeckameyerDept. of Pharmacological and Physiological Science, St. Louis Univ. School of Medicine, St. Louis, MO 63104, USA. neckamws@slu.edu
Kathryn J Argue
Saint Louis University · US

Funding

Hormonal Factors and Recruitment of Neurons into the Stress Response CircuitryR01MH083771 · NIMH · SAINT LOUIS UNIVERSITY · PI NECKAMEYER, WENDI S · 2009 to 2010
$562k
NIMH NIH HHS R01MH083771
6 · The paper itself

Abstract

Numerous studies have detailed the extensive conservation of developmental signaling pathways between the model system, Drosophila melanogaster, and mammalian models, but researchers have also profited from the unique and highly tractable genetic tools available in this system to address critical questions in physiology. In this review, we have described contributions that Drosophila researchers have made to mathematical dynamics of pattern formation, cardiac pathologies, the way in which pain circuits are integrated to elicit responses from sensation, as well as the ways in which gene expression can modulate diverse behaviors and shed light on human cognitive disorders. The broad and diverse array of contributions from Drosophila underscore its translational relevance to modeling human disease.

Indexed as

Models, AnimalModels, BiologicalAnimalsDrosophila melanogasterDrosophila ProteinsHumansMorphogenesisPhysiology, ComparativeDrosophila Proteins

Identifiers

PMID23220476
PMCPMC3567352
OpenAlexW1967661946

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.