Evidence map›Paper›PMID 23219158›Full record

ReviewVeterinary immunology and immunopathology2013

SOCS proteins in infectious diseases of mammals.

Mario Delgado-Ortega, Daniel Marc, Joëlle Dupont, Sascha Trapp, Mustapha Berri, François Meurens

Abstract readReview
In one paragraph

Review in Veterinary immunology and immunopathology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 57 citations in OpenAlex.

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  16. Comparative Integrated Omics Analysis of the Hfq Regulon inInternational journal of molecular sciences · 2019
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  19. Type I Interferon Induced byFrontiers in immunology · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Mario Delgado-OrtegaInstitut National de la Recherche Agronomique (INRA), UMR1282 Infectiologie et Santé Publique, F-37380 Nouzilly, France.
Daniel Marc
Joëlle Dupont
Sascha Trapp
Mustapha Berri
François Meurens
Infectiologie Animale et Santé Publique · FRUniversité de Tours · FRPhysiologie de la Reproduction et des Comportements · FRUniversity of Saskatchewan · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As for most biological processes, the immune response to microbial infections has to be tightly controlled to remain beneficial for the host. Inflammation is one of the major consequences of the host's immune response. For its orchestration, this process requires a fine-tuned interplay between interleukins, endothelial cells and various types of recruited immune cells. Suppressors of cytokine signalling (SOCS) proteins are crucially involved in the complex control of the inflammatory response through their actions on various signalling pathways including the JAK/STAT and NF-κB pathways. Due to their cytokine regulatory functions, they are frequent targets for exploitation by infectious agents trying to escape the host's immune response. This review article aims to summarize our current knowledge regarding SOCS family members in the different mammalian species studied so far, and to display their complex molecular interactions with microbial pathogens.

Indexed as

Amino Acid SequenceAnimalsBacterial InfectionsHumansImmunologic FactorsInfectionsMammalsModels, MolecularMolecular Sequence DataParasitic Diseases, AnimalSequence Homology, Amino AcidSignal TransductionSuppressor of Cytokine Signaling ProteinsVirus DiseasesImmunologic FactorsSuppressor of Cytokine Signaling Proteins

Identifiers

PMID23219158
PMCPMC7112700
OpenAlexW2071508840

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.