Trial reportThe American journal of cardiology2013
Sleep duration and risk of atrial fibrillation (from the Physicians' Health Study).
Trial report in The American journal of cardiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 5 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Analyzing the impact of sleep duration on atrial fibrillation risk: a comprehensive systematic review and meta-analysis.Irish journal of medical science · 2024Pooled it
- Pooled it
- Sleep Duration/Quality With Health Outcomes: An Umbrella Review of Meta-Analyses of Prospective Studies.Frontiers in medicine · 2021Pooled it
- Association between Sleep Apnea Hypopnea Syndrome and the Risk of Atrial Fibrillation: A Meta-Analysis of Cohort Study.BioMed research international · 2018Pooled it
- Sleep duration and risk of fatal and nonfatal stroke: a prospective study and meta-analysis.Neurology · 2015Pooled it
- Influence of sleep architectural disruptions on the evolution of atrial fibrillation.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025Article
- Polysomnographic sleep architectural disruption associated with atrial fibrillation development.Sleep · 2025Article
- Wristwatch pulse wave monitoring: assessing daily activity post-catheter ablation for atrial fibrillation.European heart journal. Digital health · 2025Article
- Insomnia is related to long-term atrial fibrillation recurrence following radiofrequency ablation.Annals of medicine · 2024Article
- Daytime Napping, Incident Atrial Fibrillation, and Dynamic Transitions With Dementia.JACC. Advances · 2024Article
- Review
- Association of sleep duration with atrial fibrillation/flutter mortality in the United States: a cross-sectional analysis.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024Article
- Exploring the effect of lifestyle behaviors and socioeconomic status on atrial fibrillation: the mediating role of 91 inflammatory cytokines.Frontiers in cardiovascular medicine · 2024Article
- Insomnia and Early Incident Atrial Fibrillation: A 16-Year Cohort Study of Younger Men and Women Veterans.Journal of the American Heart Association · 2023Article
- Long Sleep Duration and Stroke-Highly Linked, Poorly Understood.Neurology international · 2023Review
- Sleep duration and atrial fibrillation risk in the context of predictive, preventive, and personalized medicine: the Suita Study and meta-analysis of prospective cohort studies.The EPMA journal · 2022Article
- Association of Sleep Duration, Midday Napping with Atrial Fibrillation in Patients with Hypertension.Clinical epidemiology · 2022Article
- Healthy Sleep Patterns and Risk of Incident Arrhythmias.Journal of the American College of Cardiology · 2021Article
- Impact of Catheter Ablation on Sleep Quality and Relationship Between Sleep Stability and Recurrence of Paroxysmal Atrial Fibrillation After Successful Ablation: 24-Hour Holter-Based Cardiopulmonary Coupling Analysis.Journal of the American Heart Association · 2020Article
- Narrative review of sleep and stroke.Journal of thoracic disease · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 5 institutions in 1 country.
Funding
Abstract
Although sleep quality and duration have been related to cardiovascular end points, little is known about the association between sleep duration and incident atrial fibrillation (AF). Hence, we prospectively examined the association between sleep duration and incident AF in a cohort of 18,755 United States male physicians. Self-reported sleep duration was ascertained during a 2002 annual follow-up questionnaire. Incident AF was ascertained through annual follow-up questionnaires. Cox regression analysis was used to estimate the relative risks of AF. The average age at baseline was 67.7 ± 8.6 years. During a mean follow-up of 6.9 ± 2.1 years, 1,468 cases of AF occurred. Using 7 hours of sleep as the reference group, the multivariate adjusted hazard ratio for AF was 1.06 (95% confidence interval 0.92 to 1.22), 1.0 (reference), and 1.13 (95% confidence interval 1.00 to 1.27) from the lowest to greatest category of sleep duration (p for trend = 0.26), respectively. In a secondary analysis, no evidence was seen of effect modification by adiposity (p for interaction = 0.69); however, prevalent sleep apnea modified the relation of sleep duration with AF (p for interaction = 0.01). From the greatest to the lowest category of sleep duration, the multivariate-adjusted hazard ratio for AF was 2.26 (95% confidence interval 1.26 to 4.05), 1.0 (reference), and 1.34 (95% confidence interval 0.73 to 2.46) for those with prevalent sleep apnea and 1.01 (95% confidence interval 0.87 to 1.16), 1.0 (reference), and 1.12 (95% confidence interval 0.99 to 1.27) for those without sleep apnea, respectively. Our data showed a modestly elevated risk of AF with long sleep duration among United States male physicians. Furthermore, a shorter sleep duration was associated with a greater risk of AF in those with prevalent sleep apnea.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.