Trial reportDevelopmental cognitive neuroscience2013
Approach bias modification in alcohol dependence: do clinical effects replicate and for whom does it work best?
Trial report in Developmental cognitive neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 159 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Can Cognitive-bias Modification Training During Inpatient Alcohol Detoxification Reduce Relapse Rates Post-discharge?
Mechanisms Underlying the Approach and Avoidance Task (AAT) in Alcoholic Inpatients
Mechanisms Underlying the Approach and Avoidance Task (AAT) in Smoking Cessation
AAT-App Trial: A Clinical Trial of a "Brain-training" Smartphone App to Help Reduce Alcohol Use in People Accessing Outpatient Alcohol Treatment
Who cites it
159 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- The Role of Serious Video Games in the Treatment of Disordered Eating Behaviors: Systematic Review.Journal of medical Internet research · 2022Pooled it
- Implicit bias to food and body cues in eating disorders: a systematic review.Eating and weight disorders : EWD · 2021Pooled it
- Cognitive Bias Modification for Behavior Change in Alcohol and Smoking Addiction: Bayesian Meta-Analysis of Individual Participant Data.Neuropsychology review · 2019Pooled it
- Alcohol-Specific Computerized Interventions to Alter Cognitive Biases: A Systematic Review of Effects on Experimental Tasks, Drinking Behavior, and Neuronal Activation.Frontiers in psychiatry · 2019Pooled it
- Effects of neuromodulation on cognitive performance in individuals exhibiting addictive behaviors: A systematic review.Drug and alcohol dependence · 2018Pooled it
- [Evidence-based psychotherapy of addictive disorders].Der Nervenarzt · 2018Pooled it
- Approach With Caution: A Pilot Randomised Controlled Trial of Approach Bias Modification for People Undergoing Residential Treatment for Methamphetamine Use Disorder.Drug and alcohol review · 2026Trial
- The effects of approach bias modification on smoking cue-reactivity in individuals who smoke: A randomized controlled fMRI study.Scientific reports · 2026Trial
- Efficacy of a personalised alcohol approach bias modification smartphone app in people accessing outpatient alcohol use disorder treatment: A randomised controlled trial.Addiction (Abingdon, England) · 2026Trial
- The Effect of Smartphone-Delivered Approach Bias Modification Training on Relapse Among Patients Leaving Residential Alcohol Treatment: A Randomised Controlled Trial.Substance abuse and rehabilitation · 2026Trial
- Smartphone-Based Approach-Avoidance Bias Modification Training for Depression: Randomized Clinical Trial.JMIR mHealth and uHealth · 2025Trial
- Approach Bias and Tobacco Craving as Mechanisms of the Effect of Approach Bias Retraining on Smoking Cessation.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025Trial
- How We Lost 90% of Participants on a Bad Bet: Results from a Pilot Randomized Controlled Trial on Cognitive Bias Modification in Problem Gamblers.Journal of gambling studies · 2024Trial
- Alcohol use in the year following approach bias modification during inpatient withdrawal: secondary outcomes from a double-blind, multi-site randomized controlled trial.Addiction (Abingdon, England) · 2022Trial
- A Pilot Study on Approach Bias Modification in Smoking Cessation: Activating Personalized Alternative Activities for Smoking in the Context of Increased Craving.International journal of behavioral medicine · 2022Trial
- The effects of response inhibition training following binge memory retrieval in young adults binge eaters: a randomised-controlled experimental study.Scientific reports · 2022Trial
- "Push it!" or "Hold it!"? A comparison of nicotine-avoidance training and nicotine-inhibition training in smokers motivated to quit.Psychopharmacology · 2022Trial
- A Personalized Approach Bias Modification Smartphone App ("SWiPE") to Reduce Alcohol Use: Open-Label Feasibility, Acceptability, and Preliminary Effectiveness Study.JMIR mHealth and uHealth · 2021Trial
- Targeted self-regulation interventions in low-income children: Clinical trial results and implications for health behavior change.Journal of experimental child psychology · 2021Trial
- Trial
99 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlcoholism is a progressive neurocognitive developmental disorder. Recent evidence shows that computerized training interventions (Cognitive Bias Modification, CBM) can reverse some of these maladaptively changed neurocognitive processes. A first clinical study of a CBM, called alcohol-avoidance training, found that trained alcoholic patients showed less relapse at one-year follow-up than control patients. The present study tested the replication of this result, and questions about mediation and moderation.
methods509 alcohol-dependent patients received treatment as usual (primarily Cognitive Behavior Therapy) inpatient treatment. Before and after treatment, the implicit approach bias was measured with the Alcohol Approach-Avoidance Task. Half of the patients were randomly assigned to CBM, the other half received treatment as usual only. Background variables, psychopathology and executive control were tested as possible moderating variables of CBM. One year after treatment, follow-up data about relapse were collected.
resultsThe group receiving CBM developed alcohol-avoidance behavior and reported significantly lower relapse rates at one-year follow-up. Change in alcohol-approach bias mediated this effect. Moderation analyses demonstrated that older patients and patients with a strong approach-bias at pretest profited most from CBM.
conclusionsCBM is a promising treatment add-on in alcohol addiction and may counter some of the maladaptive neurocognitive effects of long-term alcoholism.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.