Evidence map›Paper›PMID 23218797›Full record

ArticleMayo Clinic proceedings2013

Increased incidence of cutaneous nontuberculous mycobacterial infection, 1980 to 2009: a population-based study.

Ashley B Wentworth, Lisa A Drage, Nancy L Wengenack, John W Wilson, Christine M Lohse

Open access · greenAbstract readVideo-Audio Media
In one paragraph

Article in Mayo Clinic proceedings, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 191 citations in OpenAlex.

  1. Article
  2. Cutaneous non-tuberculous mycobacterial infections: A retrospective study of 94 cases from Germany.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2026
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  9. Unusual Presentation ofCase reports in infectious diseases · 2025
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  12. Extrapulmonary Comparisons BetweenInfection and drug resistance · 2025
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  13. Case Report: CutaneousFrontiers in medicine · 2025
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  14. Toward better cures forClinical microbiology reviews · 2024
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  15. Genome sequences ofMicrobiology resource announcements · 2024
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  16. Beauty's Betrayal:Infectious disease reports · 2024
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  17. Nontuberculous mycobacterial infection in Wisconsin children and adolescents.Journal of clinical tuberculosis and other mycobacterial diseases · 2024
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  20. Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ashley B WentworthMayo Medical School, Mayo Clinic, Rochester, MN 55905, USA.
Lisa A Drage
Nancy L Wengenack
John W Wilson
Christine M Lohse
Mayo Clinic in Arizona · USMayo Clinic · US

Funding

Rochester Epidemiology ProjectR01AG034676 · NIA · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A, ST SAUVER, JENNIFER LYNN · 2010 to 2019
$9.5M
NIA NIH HHS R01 AG034676NIA NIH HHS R01AG034676
6 · The paper itself

Abstract

objectivesTo determine the incidence and clinical characteristics of cutaneous nontuberculous mycobacterial (NTM) infection during the past 30 years and whether the predominant species have changed. PATIENTS AND

methodsUsing Rochester Epidemiology Project data, we identified Olmsted County, Minnesota, residents with cutaneous NTM infections between January 1, 1980, and December 31, 2009, examining the incidence of infection, patient demographic and clinical features, the mycobacterium species, and therapy.

resultsForty patients (median age, 47 years; 58% female [23 of 40]) had positive NTM cultures plus 1 or more clinical signs. The overall age- and sex-adjusted incidence of cutaneous NTM infection was 1.3 per 100,000 person-years (95% CI, 0.9-1.7 per 100,000 person-years). The incidence increased with age at diagnosis (P=.003) and was higher in 2000 to 2009 (2.0 per 100,000 person-years; 95% CI, 1.3-2.8 per 100,000 person-years) than in 1980 to 1999 (0.7 per 100,000 person-years; 95% CI, 0.3-1.1 per 100,000 person-years) (P=.002). The distal extremities were the most common sites of infection (27 of 39 patients [69%]). No patient had human immunodeficiency virus infection, but 23% (9 of 39) were immunosuppressed. Of the identifiable causes, traumatic injuries were the most frequent (22 of 29 patients [76%]). The most common species were Mycobacterium marinum (17 of 38 patients [45%]) and Mycobacterium chelonae/Mycobacterium abscessus (12 of 38 patients [32%]). In the past decade (2000-2009), 15 of 24 species (63%) were rapidly growing mycobacteria compared with only 4 of 14 species (29%) earlier (1980-1999) (P=.04).

conclusionThe incidence of cutaneous NTM infection increased nearly 3-fold during the study period. Rapidly growing mycobacteria were predominant during the past decade.

Indexed as

AdolescentAdultAgedAged, 80 and overChildFemaleHumansIncidenceMaleMiddle AgedMinnesotaMycobacterium Infections, NontuberculousNontuberculous MycobacteriaUnited States

Identifiers

PMID23218797
PMCPMC3690780
OpenAlexW2080239293

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.