Evidence map›Paper›PMID 23218449›Full record

Trial reportInternational journal of medical informatics2013

An asthma management system in a pediatric emergency department.

Judith W Dexheimer, Thomas J Abramo, Donald H Arnold, Kevin B Johnson, Yu Shyr, Fei Ye, Kang-Hsien Fan, Neal Patel, Dominik Aronsky

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in International journal of medical informatics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04929626 (Comparison of Doses of Nebulized Magnesium Sulphate as an Adjuvant Treatment With Salbutamol in Children With Status Asthmaticus), which is not on this map. Cited by 16 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04929626 phase1completednot on this mapstarted 2022, after this paper: background citation

Comparison of Doses of Nebulized Magnesium Sulphate as an Adjuvant Treatment With Salbutamol in Children With Status Asthmaticus

TypeinterventionalSponsorZiauddin UniversityRan2022 to 2022Enrolled126ConditionsStatus AsthmaticusArmsMagnesium Sulfate 500 mg/ml+ ventolin, Ventolin
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. The role of information systems in emergency department decision-making-a literature review.Journal of the American Medical Informatics Association : JAMIA · 2024
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Asthma-related emergency department use: current perspectives.Open access emergency medicine : OAEM · 2016
    Review
  15. Clinical pathway improves pediatrics asthma management in the emergency department and reduces admissions.The Journal of asthma : official journal of the Association for the Care of Asthma · 2015
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Judith W DexheimerDivision of Emergency Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229-3039, USA. Judith.Dexheimer@cchmc.org
Thomas J Abramo
Donald H Arnold
Kevin B Johnson
Yu Shyr
Fei Ye
Kang-Hsien Fan
Neal Patel
Dominik Aronsky

Funding

Vanderbilt Biomedical Informatics Training ProgramT15LM007450 · NLM · VANDERBILT UNIVERSITY · PI Jessica S. Ancker, Bradley A. Malin · 2002 to 2026
$19.7M
Development of a Pediatric Acute Asthma Prediction Rule for severity and outcomeK23HL080005 · NHLBI · VANDERBILT UNIVERSITY · PI ARNOLD, DONALD HAYES · 2008 to 2012
$738k
An Informatics-Based Guideline Implementation Framework for Asthma CareR21LM009747 · NLM · VANDERBILT UNIVERSITY · PI ARONSKY, DOMINIK · 2008 to 2009
$379k
NHLBI NIH HHS K23 HL080005NHLBI NIH HHS K23 HL80005NLM NIH HHS LM 009747-01NLM NIH HHS R21 LM009747NLM NIH HHS T15 LM007450NLM NIH HHS T15 LM 007450-03
6 · The paper itself

Abstract

introductionPediatric asthma exacerbations account for >1.8 million emergency department (ED) visits annually. Asthma guidelines are intended to guide time-dependent treatment decisions that improve clinical outcomes; however, guideline adherence is inadequate. We examined whether an automatic disease detection system increases clinicians' use of paper-based guidelines and decreases time to a disposition decision.

methodsWe evaluated a computerized asthma detection system that triggered NHLBI-adopted, evidence-based practice to improve care in an urban, tertiary care pediatric ED in a 3-month (7/09-9/09) prospective, randomized controlled trial. A probabilistic system screened all ED patients for acute asthma. For intervention patients, the system generated the asthma protocol at triage for intervention patients to guide early treatment initiation, while clinicians followed standard processes for control patients. The primary outcome measures included time to patient disposition.

resultsThe system identified 1100 patients with asthma exacerbations, of which 704 had a final asthma diagnosis determined by a physician-established reference standard. The positive predictive value for the probabilistic system was 65%. The median time to disposition decision did not differ among the intervention (289 min; IQR = (184, 375)) and control group (288 min; IQR = (185, 375)) (p=0.21). The hospital admission rate was unchanged between intervention (37%) and control groups (35%) (p = 0.545). ED length of stay did not differ among the intervention (331 min; IQR = (226, 581)) and control group (331 min; IQR = (222, 516)) (p = 0.568).

conclusionDespite a high level of support from the ED leadership and staff, a focused education effort, and implementation of an automated disease detection, the use of the paper-based asthma protocol remained low and time to patient disposition did not change.

Indexed as

Clinical ProtocolsPediatricsAsthmaChildEmergency Service, HospitalEvidence-Based PracticeHumansPractice Guidelines as TopicReminder Systems

Identifiers

PMID23218449
PMCPMC3646328

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.