ArticleBMC pulmonary medicine2012
Confirmatory spirometry for adults hospitalized with a diagnosis of asthma or chronic obstructive pulmonary disease exacerbation.
Article in BMC pulmonary medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 33 citations in OpenAlex.
- A prospective study of chronic obstructive pulmonary disease and the risk for mild cognitive impairment.JAMA neurology · 2014Trial
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- A Research Agenda to Improve Outcomes in Patients with Chronic Obstructive Pulmonary Disease and Cardiovascular Disease: An Official American Thoracic Society Research Statement.American journal of respiratory and critical care medicine · 2024Article
- Contribution of small airway inflammation to the development of COPD.BMC pulmonary medicine · 2024Article
- Management of acute COPD exacerbations in Australia: do we follow the guidelines?ERJ open research · 2020Article
- Under- and over-diagnosis of COPD: a global perspective.Breathe (Sheffield, England) · 2019Review
- Reducing Chronic Obstructive Pulmonary Disease Hospital Readmissions. An Official American Thoracic Society Workshop Report.Annals of the American Thoracic Society · 2019Article
- A comprehensive care plan that reduces readmissions after acute exacerbations of COPD.Respiratory medicine · 2018Observational
- Spirometry in Hospitalized Patients with Acute Exacerbation of COPD Accurately Predicts Post Discharge Airflow Obstruction.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2018Article
- Effectiveness of Umeclidinium-Vilanterol for Protocolized Management of Chronic Obstructive Pulmonary Disease Exacerbation in Hospitalized Patients: A Sequential Period Analysis.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2018Article
- Reliability and usefulness of spirometry performed during admission for COPD exacerbation.PloS one · 2018Article
- Overdiagnosis of COPD in hospitalized patients.International journal of chronic obstructive pulmonary disease · 2017Article
- Estimating the extent and economic impact of under and overdiagnosis of chronic obstructive pulmonary disease in primary care.Chronic respiratory disease · 2016Observational
- Observational
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- Multicenter study comparing case definitions used to identify patients with chronic obstructive pulmonary disease.American journal of respiratory and critical care medicine · 2014Article
- Chronic obstructive pulmonary disease and association with mild cognitive impairment: the Mayo Clinic Study of Aging.Mayo Clinic proceedings · 2013Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundObjective measurement of airflow obstruction by spirometry is an essential part of the diagnosis of asthma or COPD. During exacerbations, the feasibility and utility of spirometry to confirm the diagnosis of asthma or chronic obstructive pulmonary disease (COPD) are unclear. Addressing these gaps in knowledge may help define the need for confirmatory testing in clinical care and quality improvement efforts. This study was designed to determine the feasibility of spirometry and to determine its utility to confirm the diagnosis in patients hospitalized with a physician diagnosis of asthma or COPD exacerbation.
methodsMulti-center study of four academic healthcare institutions. Spirometry was performed in 113 adults admitted to general medicine wards with a physician diagnosis of asthma or COPD exacerbation. Two board-certified pulmonologists evaluated the spirometry tracings to determine the proportion of patients able to produce adequate quality spirometry data. Findings were interpreted to evaluate the utility of spirometry to confirm the presence of obstructive lung disease, according to the 2005 European Respiratory Society/American Thoracic Society recommendations.
resultsThere was an almost perfect agreement for acceptability (κ = 0.92) and reproducibility (κ =0.93) of spirometry tracings. Three-quarters (73%) of the tests were interpreted by both pulmonologists as being of adequate quality. Of these adequate quality tests, 22% did not present objective evidence of obstructive lung disease. Obese patients (BMI ≥30 kg/m2) were more likely to produce spirometry tracings with no evidence of obstructive lung disease, compared to non-obese patients (33% vs. 8%, p = 0.007).
conclusionsAdequate quality spirometry can be obtained in most hospitalized adults with a physician diagnosis of asthma or COPD exacerbation. Confirmatory spirometry could be a useful tool to help reduce overdiagnosis of obstructive lung disease, especially among obese patients.
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