ArticleBMC gastroenterology2012
Percutaneous ultrasonographically guided liver punctures: an analysis of 1961 patients over a period of ten years.
Article in BMC gastroenterology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 83 citations in OpenAlex.
- Incidence of Complications from Percutaneous Biopsy in Chronic Liver Disease: A Systematic Review and Meta-Analysis.Digestive diseases and sciences · 2022Pooled it
- A Rare Case of Obstructive Jaundice Secondary to Hemobilia Post Endoscopic Ultrasound Guided Liver Biopsy.DEN open · 2026Article
- Advances in the prevention and management of procedural bleeding in patients with cirrhosis.Hepatology international · 2025Review
- Highest 3-month international normalized ratio (INR): a predictor of bleeding following ultrasound-guided liver biopsy.European radiology · 2024Article
- Advances of surgical robotics: image-guided classification and application.National science review · 2024Review
- Unveiling the impact of psoriasis on liver health: does methotrexate play a villainous role?Archives of dermatological research · 2024Article
- Impact of CT texture analysis on complication rate in CT-guided liver biopsies.Clinical and experimental hepatology · 2024Article
- Ultrasound-guided percutaneous biopsy for focal liver lesions: Adverse events and diagnostic yield in a single-centre analysis.PloS one · 2024Article
- Major complications after ultrasound-guided liver biopsy: An annual audit of a Chinese tertiary-care teaching hospital.World journal of gastrointestinal surgery · 2023Article
- Liver biopsy technique in the era of genomic cancer therapies: a single-center retrospective analysis.International journal of clinical oncology · 2022Article
- Liver biopsy complication rates in patients with non-alcoholic fatty liver disease.Canadian liver journal · 2022Article
- Hemorrhagic shock necessitating resuscitation and damage control surgery after needle biopsy: A report of two cases.Trauma case reports · 2021Article
- Evaluation of Risk Factors for Bleeding After Ultrasound-Guided Liver Biopsy.International journal of general medicine · 2021Article
- Analysis of Risk Factors of Bleeding Complications in Percutaneous Needle Biopsy of Liver Occupying Lesions.International journal of general medicine · 2021Article
- [Percutaneous liver biopsy before organ removal-Impact on organ allocation and costs in liver transplantation].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021Article
- A new predictor of bleeding based on ultrasonographic features in percutaneous liver mass biopsyTurkish journal of medical sciences · 2020Article
- Targeted and non-targeted liver biopsies carry the same risk of complication.European radiology · 2019Article
- Limited applicability of cathepsin D for the diagnosis and monitoring of non-alcoholic steatohepatitis.JGH open : an open access journal of gastroenterology and hepatology · 2019Article
- Impact factors for safety, success, duration and radiation exposure in CT-guided interventions.The British journal of radiology · 2019Article
- Predictors of bleeding complications following percutaneous image-guided liver biopsy: a scoping review.Diagnostic and interventional radiology (Ankara, Turkey) · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUltrasonographically guided punctures of the liver represent a decisive tool in the diagnosis of many diseases of the liver. Objective of the study was to determine the extent to which the complication rate for ultrasonographically guided punctures of the liver is affected by less comprehensively studied risk factors.
methodsA total of 2,229 liver biopsies were performed in 1,961 patients (55.5% males; 44.5% females). We recorded actual complications and assessed the following risk factors: needle gauge, puncture technique, examiner experience, coagulation status, puncture target (focal lesion versus parenchyma), lesion size, patient sex and age.
resultshe rate of complications stood at 1.2% (n = 27), of which 0.5% (n = 12) were major and 0.7% (n = 15) minor complications. A significant increase in complications involving bleeding was observed with larger-gauge needles compared with smaller-gauge needles and for cutting biopsy punctures compared with aspiration biopsies (Menghini technique). In the bivariate analysis complications were 2.7 times more frequent in procedures performed by experienced examiners compared with those with comparatively less experience. Lower values for Quick's test and higher partial thromboplastin times were associated with a higher rate of bleeding. Neither the puncture target, lesion size or patient sex exerted any measurable influence on the puncture risk. Advanced patient age was associated with a higher rate of complications involving bleeding.
conclusionsOur study helps to establish the importance of potential and less comprehensively studied risk factors and may contribute to further reduction in complications rates in routine clinical practice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.