ArticleOrganic letters2012
Total syntheses of kealiinines A-C.
Article in Organic letters, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Natural Antifungal Alkaloids for Crop Protection: An Overview of the Latest Synthetic Approaches.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Investigation of Dearomatizing Spirocyclizations and Spirocycle Functionalization En Route to Spirocalcaridines A and B-Some Trials and Tribulations.Molecules (Basel, Switzerland) · 2025Article
- Marine Natural Products from Indonesian Waters.Marine drugs · 2019Review
- Review
- Total synthesis and cytotoxicity of Leucetta alkaloids.Bioorganic & medicinal chemistry · 2017Article
- Synthesis of Naamidine A and Selective Access to N(2)-Acyl-2-aminoimidazole Analogues.The Journal of organic chemistry · 2015Article
- Studies Towards theEuropean journal of organic chemistry · 2015Article
- Total synthesis of 7'-desmethylkealiiquinone, 4'-desmethoxykealiiquinone, and 2-deoxykealiiquinone.The Journal of organic chemistry · 2014Article
- Total syntheses and cytotoxicity of kealiiquinone, 2-deoxy-2-aminokealiiquinone and analogs.Bioorganic & medicinal chemistry letters · 2013Article
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5 authors.
Funding
Abstract
Short total syntheses of the Leucetta-derived alkaloids, kealiinines A-C, have been accomplished using an intramolecular Friedel-Crafts-dehydration sequence of a bis benzylic diol. The precursor diol was obtained through a series of position-specific Grignard reactions from 1-methyl-4,5-diiodoimidazole. C2-Azidation and hydrogenation of the azide then provided the reported structures of kealiinines A-C. While the (1)H NMR data did not completely match for these materials, the HPLC data were consistent with the assigned structure of these alkaloids.
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