Evidence map›Paper›PMID 23215004›Full record

ReviewMolecular pharmaceutics2013

Mesenchymal stem cell-based therapy.

Vaibhav Mundra, Ivan C Gerling, Ram I Mahato

Abstract readReview
In one paragraph

Review in Molecular pharmaceutics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 133 citations in OpenAlex.

  1. Review
  2. Nonantibiotic Treatment of Clinical Multidrug-Resistant Bacterial Isolates Using Chitosan Nanoparticles as a Carrier for the Supernatant of Mesenchymal Stem Cells.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
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5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Vaibhav MundraDepartment of Pharmaceutical Sciences, University of Tennessee Health Science Center, Memphis, Tennessee 38103, United States.
Ivan C Gerling
Ram I Mahato
University of Tennessee Health Science Center · US

Funding

Growth Factor and Antiapoptotic Gene Delivery to Human IsletsR01DK069968 · NIDDK · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI MAHATO, RAM I. · 2005 to 2012
$2.2M
NIDDK NIH HHS R01 DK069968NIDDK NIH HHS R01 DK69968
6 · The paper itself

Abstract

Mesenchymal stem cells (MSCs) are multipotent adult stem cells which have self-renewal capacity and differentiation potential into several mesenchymal lineages including bones, cartilages, adipose tissues and tendons. MSCs may repair tissue injuries and prevent immune cell activation and proliferation. Immunomodulation and secretion of growth factors by MSCs have led to realizing the true potential of MSC-based cell therapy. The use of MSCs as immunomodulators has been explored in cell/organ transplant, tissue repair, autoimmune diseases, and prevention of graft vs host disease (GVHD). This review focuses on the clinical applications of MSC-based cell therapy, with particular emphasis on islet transplantation for treating type I diabetes.

Indexed as

AnimalsHumansImmunomodulationMesenchymal Stem CellsMesenchymal Stem Cell Transplantation

Identifiers

PMID23215004
PMCPMC3549356
OpenAlexW1987479692

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.