ArticleApplied physics letters2012
A biomimetic mechanism for antibody immobilization on lipid nanofibers for cell capture.
Article in Applied physics letters, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
4 citing papers in PubMed.
- Electrospun Nanofibers for Cancer Therapy.Advances in experimental medicine and biology · 2021Review
- Emerging Roles of Electrospun Nanofibers in Cancer Research.Advanced healthcare materials · 2018Review
- Lipid-mediated protein functionalization of electrospun polycaprolactone fibers.EXPRESS polymer letters · 2016Article
- Comparative study of antibody immobilization mediated by lipid and polymer fibers.Colloids and surfaces. B, Biointerfaces · 2015Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
The immobilization of membrane-bound molecules on organic-inorganic cholesteryl-succinyl silane (CSS) nanofibers is investigated. Fluorescent microscopy and a cell capture assay confirm the stable and functional immobilization of membrane-bound antibodies and imaging agents on the electrospun CSS nanofibers. An insert-and-tighten mechanism is proposed for the observed hydration-induced reduction in lipid nanofiber diameter, the immobilization of membrane-bound molecules, and the improved efficiency of cell capture by the functionalized CSS nanofibers over their film counterparts. The ability to stably and functionally immobilize membrane-bound molecules on the CSS nanofibers presents a promising method to functionalize lipid-based nanomaterials.
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Registered trials
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