ArticlePediatric radiology2013
Small-bowel MRI in children and young adults with Crohn disease: retrospective head-to-head comparison of contrast-enhanced and diffusion-weighted MRI.
Article in Pediatric radiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Apparent diffusion coefficient for assessing Crohn's disease activity: a meta-analysis.European radiology · 2023Pooled it
- Assessment of Activity of Crohn Disease by Diffusion-Weighted Magnetic Resonance Imaging.Medicine · 2015Trial
- Diffusion-weighted imaging in Crohn's disease.Radiologie (Heidelberg, Germany) · 2023Review
- DWI ratios: New indexes for Crohn's disease activity at magnetic resonance enterography?La Radiologia medica · 2023Article
- Usefulness of Colon Assessment by Magnetic Resonance Enterography in Pediatric Patients with Inflammatory Bowel Disease-Retrospective Case Series.Journal of clinical medicine · 2021Article
- Comparison between Diffusion-Weighted Sequences with Selective and Non-Selective Fat Suppression in the Evaluation of Crohn's Disease Activity: Are They Equally Useful?Diagnostics (Basel, Switzerland) · 2020Article
- Detection of Crohn's disease with diffusion images versus contrast-enhanced images in pediatric using MR enterography with histopathological correlation.La Radiologia medica · 2019Article
- Assessment of normal jejunum with diffusion-weighted imaging on MRE in children.Pediatric radiology · 2018Article
- Can diffusion weighting replace gadolinium enhancement in magnetic resonance enterography for inflammatory bowel disease in children?Pediatric radiology · 2018Article
- Diagnostic performance of PET/MR in the evaluation of active inflammation in Crohn disease.American journal of nuclear medicine and molecular imaging · 2018Article
- Motion-robust parameter estimation in abdominal diffusion-weighted MRI by simultaneous image registration and model estimation.Medical image analysis · 2017Article
- Colonic inflammation in pediatric inflammatory bowel disease: detection with magnetic resonance enterography.Pediatric radiology · 2017Article
- Advanced imaging techniques in pediatric body MRI.Pediatric radiology · 2017Review
- CAIPIRINHA-accelerated T1w 3D-FLASH for small-bowel MR imaging in pediatric patients with Crohn's disease: assessment of image quality and diagnostic performance.World journal of pediatrics : WJP · 2016Article
- Diffusion-weighted imaging in pediatric body magnetic resonance imaging.Pediatric radiology · 2016Review
- Features and perspectives of MR enterography for pediatric Crohn disease assessment.La Radiologia medica · 2016Article
- Article
- Value of diffusion-weighted imaging when added to magnetic resonance enterographic evaluation of Crohn disease in children.Pediatric radiology · 2016Article
- The Role of MR Enterography in Assessing Crohn's Disease Activity and Treatment Response.Gastroenterology research and practice · 2016Review
- Prospective evaluation of free-breathing diffusion-weighted imaging for the detection of inflammatory bowel disease with MR enterography in childhood population.The British journal of radiology · 2016Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSmall-bowel MRI based on contrast-enhanced T1-weighted sequences has been challenged by diffusion-weighted imaging (DWI) for detection of inflammatory bowel lesions and complications in patients with Crohn disease.
objectiveTo evaluate free-breathing DWI, as compared to contrast-enhanced MRI, in children, adolescents and young adults with Crohn disease. MATERIALS AND
methodsThis retrospective study included 33 children and young adults with Crohn disease ages 17 ± 3 years (mean ± standard deviation) and 27 matched controls who underwent small-bowel MRI with contrast-enhanced T1-weighted sequences and DWI at 1.5 T. The detectability of Crohn manifestations was determined. Concurrent colonoscopy as reference was available in two-thirds of the children with Crohn disease.
resultsDWI and contrast-enhanced MRI correctly identified 32 and 31 patients, respectively. All 22 small-bowel lesions and all Crohn complications were detected. False-positive findings (two on DWI, one on contrast-enhanced MRI), compared to colonoscopy, were a result of large-bowel lumen collapse. Inflammatory wall thickening was comparable on DWI and contrast-enhanced MRI. DWI was superior to contrast-enhanced MRI for detection of lesions in 27% of the assessed bowel segments and equal to contrast-enhanced MRI in 71% of segments.
conclusionDWI facilitates fast, accurate and comprehensive workup in Crohn disease without the need for intravenous administration of contrast medium. Contrast-enhanced MRI is superior in terms of spatial resolution and multiplanar acquisition.
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