ArticlePediatric nephrology (Berlin, Germany)2013
Risk factors for urinary stones in healthy schoolchildren with and without a family history of nephrolithiasis.
Article in Pediatric nephrology (Berlin, Germany), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 34 citations in OpenAlex.
- Maternal family history of urolithiasis is associated with earlier age of onset of stone disease.World journal of urology · 2023Article
- Article
- Effect of sample time on urinary lithogenic risk indexes in healthy and stone-forming adults and children.BMC urology · 2018Article
- Urinary stone risk factors in the descendants of patients with kidney stone disease.Pediatric nephrology (Berlin, Germany) · 2018Article
- Urinary excretion of calcium, magnesium, phosphate, citrate, oxalate, and uric acid by healthy schoolchildren using a 12-h collection protocol.Pediatric nephrology (Berlin, Germany) · 2014Article
- Surgical treatment methods of urolithiasis in the pediatric population.Developmental period medicineReview
- Mini-percutaneous nephrolithotomy in a child with multiple urogenital anomalies and a solitary duplex kidney.International braz j urol : official journal of the Brazilian Society of UrologyArticle
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe prevalence of lithiasis is increasing at all ages. This study aimed to assess the crystallization risk in urine from healthy school children and to determine urinary parameters that are most associated with it.
methodsUrine samples were obtained from 184 children aged 5-12 years: a spot sample collected in the afternoon, and a 12-h overnight sample. Information was obtained regarding family histories of lithiasis. Urine volume, pH, and biochemical parameters of stone risk were measured. Crystallization risk was defined by the presence of specific urine conditions that had previously been associated with stone formation in vitro.
resultsCrystallization risk was observed in 15 % of spot urine samples and 54 % of 12-h samples. Metabolic abnormalities and a low urinary volume were more frequently detected in children with crystallization risk. Calcium excretion and calcium/citrate ratio were higher in children with a family history of lithiasis.
conclusionsWe observed a high prevalence of crystallization risk in urine, especially in children with a family history of the disease. Low urinary volume was the factor most associated with increased risk. Adequate fluid intake at an early age may be a simple and effective measure to reduce the incidence of nephrolithiasis.
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