Evidence map›Paper›PMID 23212465›Full record

ArticleInternational journal of hematology2013

18F-FDG uptake in primary gastric malignant lymphoma correlates with glucose transporter 1 expression and histologic malignant potential.

Yuko Watanabe, Hiroaki Suefuji, Yasumitsu Hirose, Hayato Kaida, Gen Suzuki, Jun Uozumi, Etsuyo Ogo, Mayumi Miura, Konomi Takasu, Kanoko Miyazaki and 5 more

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Article in International journal of hematology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Is There a Role for [Cancers · 2022
    Article
  3. Article
  4. Prognostic Impact of Pretreatment 2-[Medicina (Kaunas, Lithuania) · 2021
    Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. 18F-FDG PET/CT in gastric MALT lymphoma: a bicentric experience.European journal of nuclear medicine and molecular imaging · 2017
    Article
  10. Article
  11. Glucose metabolism in gastric cancer: The cutting-edge.World journal of gastroenterology · 2016
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Yuko WatanabeDepartment of Radiology, Kurume University School of Medicine, 67 Asahi-Machi, Kurume, Fukuoka, Japan.
Hiroaki Suefuji
Yasumitsu Hirose
Hayato Kaida
Gen Suzuki
Jun Uozumi
Etsuyo Ogo
Mayumi Miura
Konomi Takasu
Kanoko Miyazaki
Keita Nakahara
Masatoshi Ishibashi
Takashi Okamura
Koichi Ohshima
Naofumi Hayabuchi
Kurume University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Positron emission tomography (PET) is used for staging and response evaluation in primary gastric lymphoma (PGL). However, the implications of [(18)F]-2-fluoro-2-deoxy-D-glucose ((18)F-FDG) uptake in PGL at first diagnosis have not been reported. The relationship between (18)F-FDG uptake and the expression of facilitative glucose transporters (GLUTs), hexokinase II (HK II), and Ki67, as well as malignant potential in PGL, was assessed in this study. We analyzed 23 patients with PGL [nine with diffuse large B-cell lymphoma (DLBCL); seven with high-grade mucosa-associated lymphoid tissue (MALT) lymphoma; and seven with low-grade MALT lymphoma]. The expression levels of GLUT1, GLUT3, HK II, and Ki67 were evaluated according to the percentage of positive area determined by immunohistochemistry. Standardized uptake values correlated significantly with pathological malignant potentials (low-grade/high-grade MALT lymphoma and DLBCL: p = 0.001-0.002), Ki67 (p < 0.001), and GLUT1 expression (p = 0.02). We determined that (18)F-FDG uptake is related to GLUT1 expression and tumor histological grade as well as Ki67 in PGL.

Indexed as

Multimodal ImagingPositron-Emission TomographyTomography, X-Ray ComputedAgedAged, 80 and overFemaleFluorodeoxyglucose F18GastroscopyGlucose Transporter Type 1Glucose Transporter Type 3HexokinaseHumansKi-67 AntigenLymphoma, Non-HodgkinMaleMiddle AgedFluorodeoxyglucose F18Glucose Transporter Type 1Glucose Transporter Type 3HexokinaseKi-67 Antigen

Identifiers

PMID23212465
OpenAlexW2094707526

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.