ArticleNature communications2012
Synaptic tagging and capture in the living rat.
Article in Nature communications, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
30 citing papers in PubMed, 72 citations in OpenAlex.
- Experience-driven competition in neural reorganization after stroke.The Journal of physiology · 2025Review
- Memory persistence enhancement by post-learning moderate exercise requires de novo protein synthesis in the dorsal hippocampus.PloS one · 2025Article
- Linking new information to a short-lasting memory trace induces consolidation in the hippocampus.iScience · 2024Article
- Synapses tagged, memories kept: synaptic tagging and capture hypothesis in brain health and disease.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- Article
- Ventral tegmental area dopamine projections to the hippocampus trigger long-term potentiation and contextual learning.Nature communications · 2024Article
- Memory allocation at the neuronal and synaptic levels.BMB reports · 2024Review
- Cell-type-specific optogenetic stimulation of the locus coeruleus induces slow-onset potentiation and enhances everyday memory in rats.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- The Structural Basis of Long-Term Potentiation in Hippocampal Synapses, Revealed by Electron Microscopy Imaging of Lanthanum-Induced Synaptic Vesicle Recycling.Frontiers in cellular neuroscience · 2022Article
- Neuropsin-dependent and -independent behavioral tagging.Neuropsychopharmacology reports · 2021Article
- A Simplified Plasticity Model Based on Synaptic Tagging and Capture Theory: Simplified STC.Frontiers in computational neuroscience · 2021Article
- Hippocampal Lateralization and Synaptic Plasticity in the Intact Rat: No Left-Right Asymmetry in Electrically Induced CA3-CA1 Long-Term Potentiation.Neuroscience · 2019Article
- On the Role of Calcium-Permeable AMPARs in Long-Term Potentiation and Synaptic Tagging in the Rodent Hippocampus.Frontiers in synaptic neuroscience · 2019Article
- Sleep deprivation impairs synaptic tagging in mouse hippocampal slices.Neurobiology of learning and memory · 2018Article
- Loss of Synaptic Tagging in the Anterior Cingulate Cortex after Tail Amputation in Adult Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Behavioral tagging and capture: long-term memory decline in middle-aged rats.Neurobiology of aging · 2018Article
- Making Memories: Why Time Matters.Frontiers in human neuroscience · 2018Review
- Substance P induces plasticity and synaptic tagging/capture in rat hippocampal area CA2.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Locus Coeruleus and Dopamine-Dependent Memory Consolidation.Neural plasticity · 2017Review
- ZIP It: Neural Silencing Is an Additional Effect of the PKM-Zeta Inhibitor Zeta-Inhibitory Peptide.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
In isolated hippocampal slices, decaying long-term potentiation can be stabilized and converted to late long-term potentiation lasting many hours, by prior or subsequent strong high-frequency tetanization of an independent input to a common population of neurons-a phenomenon known as 'synaptic tagging and capture'. Here we show that the same phenomenon occurs in the intact rat. Late long-term potentiation can be induced in CA1 during the inhibition of protein synthesis if an independent input is strongly tetanized beforehand. Conversely, declining early long-term potentiation induced by weak tetanization can be converted into lasting late long-term potentiation by subsequent strong tetanization of a separate input. These findings indicate that synaptic tagging and capture is not limited to in vitro preparations; the past and future activity of neurons has a critical role in determining the persistence of synaptic changes in the living animal, thus providing a bridge between cellular studies of protein synthesis-dependent synaptic potentiation and behavioural studies of memory persistence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.