Trial reportPediatric dentistry
Comparison of gray mineral trioxide aggregate and diluted formocresol in pulpotomized primary molars: a 6- to 24-month observation.
Trial report in Pediatric dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Evidence of pulpotomy in primary teeth comparing MTA, calcium hydroxide, ferric sulphate, and electrosurgery with formocresol.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2015Pooled it
- Mineral trioxide aggregate versus formocresol pulpotomy: a systematic review and meta-analysis of randomized clinical trials.Clinical oral investigations · 2014Pooled it
- Comparison of indirect pulp treatment and iRoot BP Plus pulpotomy in primary teeth with extremely deep caries: a prospective randomized trial.Clinical oral investigations · 2021Trial
- BiodentineBMC oral health · 2019Trial
- Success Rates of Pulpotomies in Primary Molars Using Calcium Silicate-Based Materials: A Randomized Control Trial.BioMed research international · 2017Trial
- Comparison of mineral trioxide aggregate and diluted formocresol in pulpotomized human primary molars: 42-month follow-up and survival analysis.Pediatric dentistryTrial
- Long-term Outcomes of Invasive Pulp Therapies in Primary Teeth: A Systematic Review and Meta-analysis.International journal of clinical pediatric dentistry · 2026Article
- Comparison of calcium silicate-based materials in pulpotomies of primary molars: a randomized clinical trial.European oral research · 2025Article
- Clinical and radiographic success of TheraCal versus Formocresol in primary teeth pulpotomy: A systematic review andThe Saudi dental journal · 2024Review
- Hyaluronic acid as a pulpotomy material in primary molars: an up to 30 months retrospective study.BMC oral health · 2024Article
- Clinical and Radiographic Evaluation of Mineral Trioxide Aggregate and Human Amniotic Membrane Pulpotomy in Primary Molars: A Randomized Clinical Trial.International journal of clinical pediatric dentistry · 2024Article
- Comparative efficacy of medicaments or techniques for pulpotomy of primary molars: a network meta-analysis.Clinical oral investigations · 2023Review
- Pulp Therapy of Primary Dentition; its Relevance despite Insufficient Histological Evidence: A Review.Iranian endodontic journal · 2023Review
- Inflammatory Status of Excavated Pulp Tissue and Internal Root Resorption in Pulpotomized Primary Molars.Journal of dentistry (Shiraz, Iran) · 2022Article
- Clinical Radiographic Evaluation of 3Mixtatin and MTA in Primary Teeth Pulpotomies: A Randomized Controlled.International journal of clinical pediatric dentistry · 2022Article
- An Update on Newer Pulpotomy Agents in Primary Teeth: A Literature Review.Journal of pharmacy & bioallied sciences · 2021Review
- Different Pulp Dressing Materials for the Pulpotomy of Primary Teeth: A Systematic Review of the Literature.Journal of clinical medicine · 2020Review
- Mineral Trioxide Aggregate and Diluted Formocresol Pulpotomy: Prospective and Retrospective Study Outcomes.The Journal of the Michigan Dental Association · 2018Article
- Comparative Evaluation of Clinical and Radiographic Success of MTA and Propolis in Pulpotomy of Primary Molars.Iranian endodontic journal · 2018Article
- Dentinogenic Specificity in the Preclinical Evaluation of Vital Pulp Treatment Strategies: A Critical Review.Dentistry journal · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
purposeThe purpose of this multisite, multioperator, prospective, randomized, controlled clinical trial was to evaluate 2-year outcomes of diluted formocresol (DFC) compared to gray mineral trioxide aggregate (GMTA) as pulpotomy medicaments.
methodsFollowing the standard pulpotomy procedure, the pulp stumps of 252 primary molars in 168 healthy children were randomly covered with GMTA or DFC. Pulp chambers were filled with Intermediate Restorative Material (IRM(®)) and teeth were restored with stainless steel crowns. At each follow-up appointment, the clinical status of the treated tooth was assessed and radiographs were taken. A total of 694 clinical and radiographic evaluations were analyzed.
resultsGender, study site, arch type, and tooth type did not influence treatment outcome. At the combined 6- to 24-month follow-up, clinical success in the DFC group was no different than for the GMTA group. Radiographically, a significantly lower success rate was found in the DFC group vs the MTA group at all time points (P<.01). Dentin bridge formation was observed at a significantly higher frequency among the GMTA group (P<.01), while internal root resorption was observed at a higher frequency in the DFC group (P<.01).
conclusionAt the combined 6- to 24-month follow-up, gray mineral trioxide aggregate demonstrated significantly better radiographic outcomes vs diluted formocresol as pulpotomy medicaments.
Indexed as
Identifiers
23211896PMC4889335W149197497What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.