ArticleTranslational neurodegeneration2012
Premotor biomarkers for Parkinson's disease - a promising direction of research.
Article in Translational neurodegeneration, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 70 citations in OpenAlex.
- Machine Learning Approaches to Early Detection of Parkinson's Disease Using Speech Analysis Technique.Neurology international · 2026Article
- Explaining facial action units' correlation with hypomimia and clinical scores in Parkinson's disease.NPJ Parkinson's disease · 2025Article
- DNA Methylation and Expression Profiles of Whole Blood in Parkinson's Disease.Frontiers in genetics · 2021Article
- X-Vectors: New Quantitative Biomarkers for Early Parkinson's Disease Detection From Speech.Frontiers in neuroinformatics · 2021Article
- Proteomics in Human Parkinson's Disease: Present Scenario and Future Directions.Cellular and molecular neurobiology · 2019Review
- Mitochondrial clearance and maturation of autophagosomes are compromised in LRRK2 G2019S familial Parkinson's disease patient fibroblasts.Human molecular genetics · 2019Article
- DNA methylation changes associated with Parkinson's disease progression: outcomes from the first longitudinal genome-wide methylation analysis in blood.Epigenetics · 2019Article
- What Have We Learned from Cerebrospinal Fluid Studies about Biomarkers for Detecting LRRK2 Parkinson's Disease Patients and Healthy Subjects with Parkinson's-Associated LRRK2 Mutations?Journal of Parkinson's disease · 2019Review
- Early Life Stress, Depression And Parkinson's Disease: A New Approach.Molecular brain · 2018Review
- Brief isoflurane anesthesia regulates striatal AKT-GSK3β signaling and ameliorates motor deficits in a rat model of early-stage Parkinson's disease.Journal of neurochemistry · 2017Article
- Microglia P2Y6 receptor is related to Parkinson's disease through neuroinflammatory process.Journal of neuroinflammation · 2017Article
- Among Early Appearing Non-Motor Signs of Parkinson's Disease, Alteration of Olfaction but Not Electroencephalographic Spectrum Correlates with Motor Function.Frontiers in neurology · 2017Article
- Current understanding of the molecular mechanisms in Parkinson's disease: Targets for potential treatments.Translational neurodegeneration · 2017Review
- Neuromolecular imaging, a nanobiotechnology for Parkinson's disease: advancing pharmacotherapy for personalized medicine.Journal of neural transmission (Vienna, Austria : 1996) · 2017Article
- Position Emission Tomography/Single-Photon Emission Tomography Neuroimaging for Detection of Premotor Parkinson's Disease.CNS neuroscience & therapeutics · 2016Review
- Methylation status of DJ-1 in leukocyte DNA of Parkinson's disease patients.Translational neurodegeneration · 2016Article
- Neuropathobiology of non-motor symptoms in Parkinson disease.Journal of neural transmission (Vienna, Austria : 1996) · 2015Review
- Low-variance RNAs identify Parkinson's disease molecular signature in blood.Movement disorders : official journal of the Movement Disorder Society · 2015Article
- Kuwaiti population subgroup of nomadic Bedouin ancestry-Whole genome sequence and analysis.Genomics data · 2015Article
- Salivary DJ-1 could be an indicator of Parkinson's disease progression.Frontiers in aging neuroscience · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The second most serious neurodegenerative disease is Parkinson's disease (PD). Over the past several decades, a strong body of evidence suggests that PD can begin years before the hallmark clinical motor symptoms appear. Biomarkers for PD are urgently needed to differentiate between neurodegenerative disorders, screen novel therapeutics, and predict eventual clinical PD before the onset of symptoms. Some clinical evaluations and neuroimaging techniques have been developed in the last several years with some success in this area. Moreover, other strategies have been utilized to identify biochemical and genetic markers associated with PD leading to the examination of PD progression and pathogenesis in cerebrospinal fluid, blood, or saliva. Finally, interesting results are surfacing from preliminary studies using known PD-associated genetic mutations to assess potential premotor PD biomarkers. The current review highlights recent advances and underscores areas of potential advancement.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.