ArticleACS nano2013
Aptamer-conjugated multifunctional nanoflowers as a platform for targeting, capture, and detection in laser desorption ionization mass spectrometry.
Article in ACS nano, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Plasmonic silver nanoshells for drug and metabolite detection.Nature communications · 2017Trial
- MALDI Matrix: Origins, Innovations, and Frontiers.Chemical reviews · 2026Review
- CRISPR-Enhanced Colorimetric Aptasensor for Adenosine Triphosphate Detection Based on MoSBiosensors · 2025Article
- UV light promoted dihydrolipoic acid and its alanine derivative directed rapid synthesis of stable gold nanoparticles and their catalytic activity.Scientific reports · 2024Article
- Role of pretty nanoflowers as novel versatile analytical tools for sensing in biomedical and bioanalytical applications.Smart medicine · 2024Review
- Nanomedicine for renal cell carcinoma: imaging, treatment and beyond.Journal of nanobiotechnology · 2023Review
- Electrochemical Aptasensor Based on Au Nanoparticles Decorated Porous Carbon Derived from Metal-Organic Frameworks for Ultrasensitive Detection of Chloramphenicol.Molecules (Basel, Switzerland) · 2022Article
- Surface-assisted laser desorption/ionization mass spectrometry imaging: A review.Mass spectrometry reviews · 2022Review
- Aptamer-conjugated graphene oxide-based surface assisted laser desorption ionization mass spectrometry for selective extraction and detection of AβFrontiers in aging neuroscience · 2022Article
- A disposable gold foil paper-based aptasensor for detection of enteropathogenic Escherichia coli with SERS analysis and magnetic separation technology.Mikrochimica acta · 2021Article
- Nanomedicine for Immunotherapy Targeting Hematological Malignancies: Current Approaches and Perspective.Nanomaterials (Basel, Switzerland) · 2021Review
- Article
- Recent Advances in the Use of Iron-Gold Hybrid Nanoparticles for Biomedical Applications.Nanomaterials (Basel, Switzerland) · 2021Review
- Design and Preparation of "corn-like" SPIONs@DFK-SBP-M13 Assembly for Improvement of Effective Internalization.International journal of nanomedicine · 2021Article
- Screening of Urinary Renal Cancer Metabolic Biomarkers with Gold Nanoparticles-assisted Laser Desorption/Ionization Mass Spectrometry.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2020Article
- RNA aptamer capture of macromolecular complexes for mass spectrometry analysis.Nucleic acids research · 2020Article
- Soft and Condensed Nanoparticles and Nanoformulations for Cancer Drug Delivery and Repurpose.Advanced therapeutics · 2020Article
- Article
- Formation of functional nanobiocatalysts with a novel and encouraging immobilization approach and their versatile bioanalytical applications.RSC advances · 2018Review
- Metabolic Fingerprinting on a Plasmonic Gold Chip for Mass Spectrometry BasedACS central science · 2018Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Although many different nanomaterials have been tested as substrates for laser desorption and ionization mass spectrometry (LDI-MS), this emerging field still requires more efficient multifuncional nanomaterials for targeting, enrichment, and detection. Here, we report the use of gold manganese oxide (Au@MnO) hybrid nanoflowers as an efficient matrix for LDI-MS. The nanoflowers were also functionalized with two different aptamers to target cancer cells and capture adenosine triphosphate (ATP). These nanoflowers were successfully used for metabolite extraction from cancer cell lysates. Thus, in one system, our multifunctional nanoflowers can (1) act as an ionization substrate for mass spectrometry, (2) target cancer cells, and (3) detect and analyze metabolites from cancer cells.
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