SynthesisInfluenza and other respiratory viruses2013
Burden of influenza in Latin America and the Caribbean: a systematic review and meta-analysis.
Synthesis in Influenza and other respiratory viruses, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The burden of seasonal influenza in Italy: A systematic review of influenza-related complications, hospitalizations, and mortality.Influenza and other respiratory viruses · 2022Pooled it
- Immunogenicity and safety of Southern Hemisphere inactivated quadrivalent influenza vaccine: a Phase III, open-label study of adults in Brazil.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious DiseasesTrial
- Article
- Annual Estimation of Seasonal Influenza Burden in 6 South American Countries: A Retrospective Analysis of SARInet Surveillance Data to Inform Policies.The Journal of infectious diseases · 2025Article
- Article
- Review
- Cost of lost productivity from acute respiratory infections in South America.Revista panamericana de salud publica = Pan American journal of public health · 2023Article
- Hospitalization and risk of death due to influenza among vaccinated and unvaccinated patients. A 5-year study in the northeastern Mexican population.Human vaccines & immunotherapeutics · 2022Article
- [Health Technology Assessment: a value-based tool for the evaluation of healthcare technologies. Reassessment of the cell-culture-derived quadrivalent influenza vaccine: Flucelvax TetraJournal of preventive medicine and hygiene · 2022Article
- Article
- Hospital admissions with influenza and impact of age and comorbidities on severe clinical outcomes in Brazil and Mexico.PloS one · 2022Article
- Economic costs of severe seasonal influenza in Colombia, 2017-2019: A multi-center analysis.PloS one · 2022Article
- A Call for a Reform of the Influenza Immunization Program in Mexico: Epidemiologic and Economic Evidence for Decision Making.Vaccines · 2021Article
- Article
- Clinical characteristics and outcomes of influenza A and B virus infection in adult Australian hospitalised patients.BMC infectious diseases · 2020Observational
- Impact of quadrivalent influenza vaccines in Brazil: a cost-effectiveness analysis using an influenza transmission model.BMC public health · 2020Article
- Influenza in the school-aged population in Mexico: burden of disease and cost-effectiveness of vaccination in children.BMC infectious diseases · 2020Article
- Improved Real-Time Influenza Surveillance: Using Internet Search Data in Eight Latin American Countries.JMIR public health and surveillance · 2019Article
- Prioritization of risk groups for influenza vaccination in resource limited settings - A case study from South Africa.Vaccine · 2019Article
- Severe acute respiratory infections (SARI) from influenza in adult patients in Chile: the experience of a sentinel hospital.Revista panamericana de salud publica = Pan American journal of public health · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveInfluenza causes severe morbidity and mortality. This systematic review aimed to assess the incidence, etiology, and resource usage for influenza in Latin America and the Caribbean.
designMeta-analytic systematic review. Arcsine transformations and DerSimonian Laird random effects model were used for meta-analyses.
settingA literature search from 1980 to 2008 in MEDLINE, Cochrane Library, EMBASE, LILACS, Ministries of Health, PAHO, proceedings, reference lists, and consulting experts. SAMPLE: We identified 1092 references, of which 31 were finally included, in addition to influenza surveillance reports. We also used information from the 10 reports from the collaborative group for epidemiological surveillance of influenza and other respiratory virus (GROG), and information retrieved from the WHO global flu database FLUNET.
main outcome measuresIncidence, percentage of influenza specimens out of the total received by influenza centers and resource-use outcomes.
resultsA total of 483 130 specimens of patients with influenza were analyzed. Meta-analysis showed an annual rate of 36 080 (95%CI 28 550 43 610) influenza-like illness per 100 000 persons-years. The percentage of influenza out of total specimens received by influenza centers ranged between 4.66% and 15.42%, with type A the most prevalent, and A subtype H3 predominating. The mean length of stay at hospital due to influenza ranged between 5.8 12.9 days, total workdays lost due to influenza-like illnesses were 17 150 days, and the mean direct cost of hospitalization was US$575 per laboratory-confirmed influenza case.
conclusionsOur data show that seasonal influenza imposes a high morbidity and economic burden to the region. However, the vaccine-uptake rate has been low in this region. Population-based cohort studies are required to improve the knowledge about incidence and resource utilization, which would inform healthcare authorities for decision making.
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