ArticlePloS one2012
Ensemble response in mushroom body output neurons of the honey bee outpaces spatiotemporal odor processing two synapses earlier in the antennal lobe.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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26 citing papers in PubMed, 42 citations in OpenAlex.
- Form informs function: innervation patterns of projection neurons correspond to response profiles of mushroom body output neurons during olfactory-visual integration.Frontiers in physiology · 2026Article
- Multi-unit recordings in the stick insectFrontiers in physiology · 2026Article
- Olfactory receptor neurons are sensitive to stimulus onset asynchrony: implications for odor source discrimination.Chemical senses · 2024Article
- Active sensing in a dynamic olfactory world.Journal of computational neuroscience · 2022Article
- Early olfactory, but not gustatory processing, is affected by the selection of heritable cognitive phenotypes in honey bee.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2021Article
- Plasticity and modulation of olfactory circuits in insects.Cell and tissue research · 2021Review
- Review
- Article
- Distributed plasticity in ant visual pathways following colour learning.Proceedings. Biological sciences · 2019Article
- Multimodal integration and stimulus categorization in putative mushroom body output neurons of the honeybee.Royal Society open science · 2018Article
- The Effect of Common Signals on Power, Coherence and Granger Causality: Theoretical Review, Simulations, and Empirical Analysis of Fruit Fly LFPs Data.Frontiers in systems neuroscience · 2018Article
- Olfactory coding in the turbulent realm.PLoS computational biology · 2017Article
- Calcium imaging revealed no modulatory effect on odor-evoked responses of the Drosophila antennal lobe by two populations of inhibitory local interneurons.Scientific reports · 2017Article
- Olfactory learning without the mushroom bodies: Spiking neural network models of the honeybee lateral antennal lobe tract reveal its capacities in odour memory tasks of varied complexities.PLoS computational biology · 2017Article
- DNA methylation mediates neural processing after odor learning in the honeybee.Scientific reports · 2017Article
- Neural correlates of side-specific odour memory in mushroom body output neurons.Proceedings. Biological sciences · 2016Article
- Olfactory system oscillations across phyla.Current opinion in neurobiology · 2015Review
- Decision-making and action selection in insects: inspiration from vertebrate-based theories.Frontiers in behavioral neuroscience · 2015Review
- Article
- Simultaneous long-term recordings at two neuronal processing stages in behaving honeybees.Journal of visualized experiments : JoVE · 2014Article
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Authors and funding
3 authors at 2 institutions in 3 countries.
Funding
Abstract
Neural representations of odors are subject to computations that involve sequentially convergent and divergent anatomical connections across different areas of the brains in both mammals and insects. Furthermore, in both mammals and insects higher order brain areas are connected via feedback connections. In order to understand the transformations and interactions that this connectivity make possible, an ideal experiment would compare neural responses across different, sequential processing levels. Here we present results of recordings from a first order olfactory neuropile - the antennal lobe (AL) - and a higher order multimodal integration and learning center - the mushroom body (MB) - in the honey bee brain. We recorded projection neurons (PN) of the AL and extrinsic neurons (EN) of the MB, which provide the outputs from the two neuropils. Recordings at each level were made in different animals in some experiments and simultaneously in the same animal in others. We presented two odors and their mixture to compare odor response dynamics as well as classification speed and accuracy at each neural processing level. Surprisingly, the EN ensemble significantly starts separating odor stimuli rapidly and before the PN ensemble has reached significant separation. Furthermore the EN ensemble at the MB output reaches a maximum separation of odors between 84-120 ms after odor onset, which is 26 to 133 ms faster than the maximum separation at the AL output ensemble two synapses earlier in processing. It is likely that a subset of very fast PNs, which respond before the ENs, may initiate the rapid EN ensemble response. We suggest therefore that the timing of the EN ensemble activity would allow retroactive integration of its signal into the ongoing computation of the AL via centrifugal feedback.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.