SynthesisPLoS medicine2012
The long-term health consequences of child physical abuse, emotional abuse, and neglect: a systematic review and meta-analysis.
Synthesis in PLoS medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 1,153 papers, 10 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Can Children be Protected Against Violence and Violations From Parents? A Randomized Controlled Study of Safer Kids: A Manualized Intervention to Prevent Child Abuse
Facing Adverse Childhood Experiences Using New Technologies
Evaluating an Educational Intervention for Improving Residents' Recognition and Response to Child Maltreatment - A Mixed Method Acceptability and Feasibility Study With a Pilot Randomized Trial
Unfolding the Wisdom Within: A Clinical Trial Assessing the Impact of a Compassion Based Psychotherapeutic Intervention for Adolescents Placed in Child-welfare-based Residential Care
Reducing Parental Substance Use, Improving Child Health Outcomes, and Enhancing Family Resilience Among Rural Families Through Ohio START (Sobriety, Treatment, and Reducing Trauma)
Who cites it
1,153 citing papers in PubMed, 10 syntheses or guidelines pooled it.
- Prospective Longitudinal Associations Between Adverse Childhood Experiences and Adult Mental Health Outcomes: Systematic Review and Meta-Analysis.Trauma, violence & abuse · 2026Pooled it
- Public Knowledge and Attitudes About the Nature and Impact of Child Emotional Abuse: A Systematic Review.Child maltreatment · 2026Pooled it
- Dimensions of early life adversity and cardiometabolic health in adulthood: A systematic review and meta-analysis.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026Pooled it
- A systematic review of the global and regional estimates of the prevalence of sexual violence against children.Nature human behaviour · 2026Pooled it
- Associations between five forms of child maltreatment and depression: a multilevel meta-analytic comparison.Psychological medicine · 2026Pooled it
- Postnatal maternal mental health-related hospitalisation and its association with adverse child health and maltreatment outcomes: narrative review.Frontiers in psychiatry · 2026Pooled it
- Psychosocial adversity and executive functions in children and adolescents: a systematic review of mediating and moderating influences of parenting behaviors.BMC psychiatry · 2025Pooled it
- The association of parental or caregiver alcohol use with child maltreatment: A systematic review and meta-analysis of longitudinal studies.Addiction (Abingdon, England) · 2025Pooled it
- Health effects associated with exposure of children to physical violence, psychological violence and neglect: a Burden of Proof study.Nature human behaviour · 2025Pooled it
- Childhood maltreatment and the risk of eating disorders: a meta-analysis of observational studies.Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2025Pooled it
- A 12-Month Trial-Based Economic Evaluation Comparing Positive Parenting Program (Triple P) and Circle of Security Parenting Program (COSP) Versus Treatment as Usual for Families With Young Children (2-6 Years).Journal of evaluation in clinical practice · 2026Trial
- Yoga as a pre-treatment of EMDR to treat childhood abuse-related PTSD: feasibility and pilot study.European journal of psychotraumatology · 2025Trial
- The Good School Toolkit-Secondary to prevent violence against students: a pilot cluster randomised controlled trial.BMC public health · 2025Trial
- Optimizing Engagement With a Smartphone App to Prevent Violence Against Adolescents: Results From a Cluster Randomized Factorial Trial in Tanzania.Journal of medical Internet research · 2025Trial
- Trauma exposure and traumatic stress in foster carers: a scoping review.European journal of psychotraumatology · 2026Review
- Germany'sEuropean journal of psychotraumatology · 2026Article
- The salient role of childhood neglect in single and multiple suicide attempts among adult psychiatric inpatients.European journal of psychotraumatology · 2026Article
- Discrepancy Between Clinical Suspicion and Legal Outcomes in Suspected Child Abuse: A 10-Year Single-Center Study.Journal of Korean medical science · 2026Article
- Adolescents' and parents' perspectives on addressing adverse childhood experiences in school-based health centers.Pediatric research · 2026Article
- Risk and resilience from early to middle childhood in three-generation families: Grandmother coresidence stability matters.Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43) · 2026Article
1,093 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChild sexual abuse is considered a modifiable risk factor for mental disorders across the life course. However the long-term consequences of other forms of child maltreatment have not yet been systematically examined. The aim of this study was to summarise the evidence relating to the possible relationship between child physical abuse, emotional abuse, and neglect, and subsequent mental and physical health outcomes. METHODS AND
findingsA systematic review was conducted using the Medline, EMBASE, and PsycINFO electronic databases up to 26 June 2012. Published cohort, cross-sectional, and case-control studies that examined non-sexual child maltreatment as a risk factor for loss of health were included. All meta-analyses were based on quality-effects models. Out of 285 articles assessed for eligibility, 124 studies satisfied the pre-determined inclusion criteria for meta-analysis. Statistically significant associations were observed between physical abuse, emotional abuse, and neglect and depressive disorders (physical abuse [odds ratio (OR) = 1.54; 95% CI 1.16-2.04], emotional abuse [OR = 3.06; 95% CI 2.43-3.85], and neglect [OR = 2.11; 95% CI 1.61-2.77]); drug use (physical abuse [OR = 1.92; 95% CI 1.67-2.20], emotional abuse [OR = 1.41; 95% CI 1.11-1.79], and neglect [OR = 1.36; 95% CI 1.21-1.54]); suicide attempts (physical abuse [OR = 3.40; 95% CI 2.17-5.32], emotional abuse [OR = 3.37; 95% CI 2.44-4.67], and neglect [OR = 1.95; 95% CI 1.13-3.37]); and sexually transmitted infections and risky sexual behaviour (physical abuse [OR = 1.78; 95% CI 1.50-2.10], emotional abuse [OR = 1.75; 95% CI 1.49-2.04], and neglect [OR = 1.57; 95% CI 1.39-1.78]). Evidence for causality was assessed using Bradford Hill criteria. While suggestive evidence exists for a relationship between maltreatment and chronic diseases and lifestyle risk factors, more research is required to confirm these relationships.
conclusionsThis overview of the evidence suggests a causal relationship between non-sexual child maltreatment and a range of mental disorders, drug use, suicide attempts, sexually transmitted infections, and risky sexual behaviour. All forms of child maltreatment should be considered important risks to health with a sizeable impact on major contributors to the burden of disease in all parts of the world. The awareness of the serious long-term consequences of child maltreatment should encourage better identification of those at risk and the development of effective interventions to protect children from violence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.