Evidence map›Paper›PMID 23209385›Full record

SynthesisPLoS medicine2012

The long-term health consequences of child physical abuse, emotional abuse, and neglect: a systematic review and meta-analysis.

Rosana E Norman, Munkhtsetseg Byambaa, Rumna De, Alexander Butchart, James Scott, Theo Vos

5 registry-linked trialsAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in PLoS medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 1,153 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,153citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04163367 nacompletednot on this mapstarted 2019, after this paper: background citation

Can Children be Protected Against Violence and Violations From Parents? A Randomized Controlled Study of Safer Kids: A Manualized Intervention to Prevent Child Abuse

TypeinterventionalSponsorKarolinska InstitutetRan2019 to 2024Enrolled112ConditionsChild Abuse, Child MaltreatmentArmsSafer Kids, Intervention as usual (IAU)
NCT05122988 completednot on this mapstarted 2021, after this paper: background citation

Facing Adverse Childhood Experiences Using New Technologies

TypeobservationalSponsorUniversity of Applied Sciences and Arts Northwestern SwitzerlandRan2021 to 2024Enrolled2,606ConditionsAdverse Childhood Experiences
NCT05490121 nacompletednot on this mapstarted 2022, after this paper: background citation

Evaluating an Educational Intervention for Improving Residents' Recognition and Response to Child Maltreatment - A Mixed Method Acceptability and Feasibility Study With a Pilot Randomized Trial

TypeinterventionalSponsorMcMaster UniversityRan2022 to 2023Enrolled84ConditionsDomestic Violence, Child Maltreatment, Pediatric ALL, PsychiatryArmsViolence, Evidence, Guidance, Action Project (VEGA) Education Intervention
NCT06219057 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Unfolding the Wisdom Within: A Clinical Trial Assessing the Impact of a Compassion Based Psychotherapeutic Intervention for Adolescents Placed in Child-welfare-based Residential Care

TypeinterventionalSponsorUniversity of CoimbraRan2023 to 2024Enrolled30ConditionsAdolescent Behavior, Adolescent - Emotional ProblemArmsThe Wise Adolescent
NCT07278427 narecruitingnot on this mapstarted 2026, after this paper: background citation

Reducing Parental Substance Use, Improving Child Health Outcomes, and Enhancing Family Resilience Among Rural Families Through Ohio START (Sobriety, Treatment, and Reducing Trauma)

TypeinterventionalSponsorOhio State UniversityRan2026 to 2030Enrolled400ConditionsSubstance Use Disorder (SUD), Rural Health, Family Resilience, Child MaltreatmentArmsOhio START (Ohio Sobriety, Treatment, and Reducing Trauma)
3 · Its place in the literature

Who cites it

1,153 citing papers in PubMed, 10 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Dimensions of early life adversity and cardiometabolic health in adulthood: A systematic review and meta-analysis.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026
    Pooled it
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  10. Childhood maltreatment and the risk of eating disorders: a meta-analysis of observational studies.Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2025
    Pooled it
  11. Trial
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  15. Review
  16. Germany'sEuropean journal of psychotraumatology · 2026
    Article
  17. Article
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  20. Risk and resilience from early to middle childhood in three-generation families: Grandmother coresidence stability matters.Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43) · 2026
    Article

1,093 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Rosana E NormanQueensland Children's Medical Research Institute, University of Queensland, Herston, Australia. r.norman@sph.uq.edu.au
Munkhtsetseg Byambaa
Rumna De
Alexander Butchart
James Scott
Theo Vos

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChild sexual abuse is considered a modifiable risk factor for mental disorders across the life course. However the long-term consequences of other forms of child maltreatment have not yet been systematically examined. The aim of this study was to summarise the evidence relating to the possible relationship between child physical abuse, emotional abuse, and neglect, and subsequent mental and physical health outcomes. METHODS AND

findingsA systematic review was conducted using the Medline, EMBASE, and PsycINFO electronic databases up to 26 June 2012. Published cohort, cross-sectional, and case-control studies that examined non-sexual child maltreatment as a risk factor for loss of health were included. All meta-analyses were based on quality-effects models. Out of 285 articles assessed for eligibility, 124 studies satisfied the pre-determined inclusion criteria for meta-analysis. Statistically significant associations were observed between physical abuse, emotional abuse, and neglect and depressive disorders (physical abuse [odds ratio (OR) = 1.54; 95% CI 1.16-2.04], emotional abuse [OR = 3.06; 95% CI 2.43-3.85], and neglect [OR = 2.11; 95% CI 1.61-2.77]); drug use (physical abuse [OR = 1.92; 95% CI 1.67-2.20], emotional abuse [OR = 1.41; 95% CI 1.11-1.79], and neglect [OR = 1.36; 95% CI 1.21-1.54]); suicide attempts (physical abuse [OR = 3.40; 95% CI 2.17-5.32], emotional abuse [OR = 3.37; 95% CI 2.44-4.67], and neglect [OR = 1.95; 95% CI 1.13-3.37]); and sexually transmitted infections and risky sexual behaviour (physical abuse [OR = 1.78; 95% CI 1.50-2.10], emotional abuse [OR = 1.75; 95% CI 1.49-2.04], and neglect [OR = 1.57; 95% CI 1.39-1.78]). Evidence for causality was assessed using Bradford Hill criteria. While suggestive evidence exists for a relationship between maltreatment and chronic diseases and lifestyle risk factors, more research is required to confirm these relationships.

conclusionsThis overview of the evidence suggests a causal relationship between non-sexual child maltreatment and a range of mental disorders, drug use, suicide attempts, sexually transmitted infections, and risky sexual behaviour. All forms of child maltreatment should be considered important risks to health with a sizeable impact on major contributors to the burden of disease in all parts of the world. The awareness of the serious long-term consequences of child maltreatment should encourage better identification of those at risk and the development of effective interventions to protect children from violence.

Indexed as

Cost of IllnessLife StyleMental HealthAdolescentAdultChildChild AbuseChronic DiseaseHumansRisk AssessmentRisk FactorsTime Factors

Identifiers

PMID23209385
PMCPMC3507962

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.