ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2013
What limits the evolutionary emergence of pathogens?
Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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Who cites it
44 citing papers in PubMed.
- Virulent Parasites Emerge in Hosts With Rising Temperatures.Global change biology · 2026Article
- Microbial Primer: Understanding the exponential growth of epidemics.Microbiology (Reading, England) · 2026Review
- Preventing Disease Emergence Following Eradication: Application to Mpox.bioRxiv : the preprint server for biology · 2026Article
- Zika Virus: A Tale of Two Lineages.Pathogens (Basel, Switzerland) · 2025Review
- Superspreading and the evolution of virulence.PLoS computational biology · 2025Article
- Individually redundant effectors are collectively required for bacterial pathogen virulence.The ISME journal · 2025Article
- Spatial clustering of hosts can favor specialist parasites.Ecology and evolution · 2024Article
- Adaptive colonization across a parasitism-mutualism gradient.Evolution letters · 2024Article
- Building pyramids against the evolutionary emergence of pathogens.Proceedings. Biological sciences · 2024Article
- Demographic feedbacks during evolutionary rescue can slow or speed adaptive evolution.Proceedings. Biological sciences · 2024Article
- Article
- Non-pharmaceutical interventions and the emergence of pathogen variants.Evolution, medicine, and public health · 2023Article
- Molecular epidemiology of the citrus bacterial pathogenEvolutionary applications · 2022Article
- The source of individual heterogeneity shapes infectious disease outbreaks.Proceedings. Biological sciences · 2022Article
- Population-level deep sequencing reveals the interplay of clonal and sexual reproduction in the fungal wheat pathogenMicrobial genomics · 2021Article
- Inferring Genome-Wide Correlations of Mutation Fitness Effects between Populations.Molecular biology and evolution · 2021Article
- Establishment versus population growth in spatio-temporally varying environments.Proceedings. Biological sciences · 2021Article
- Experimental Evolution in Plant-Microbe Systems: A Tool for Deciphering the Functioning and Evolution of Plant-Associated Microbial Communities.Frontiers in microbiology · 2021Review
- Genetic analysis reveals long-standing population differentiation and high diversity in the rust pathogen Melampsora lini.PLoS pathogens · 2020Article
- Article
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4 authors.
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Abstract
The ability of a pathogen to cause an epidemic when introduced in a new host population often relies on its ability to adapt to this new environment. Here, we give a brief overview of recent theoretical and empirical studies of such evolutionary emergence of pathogens. We discuss the effects of several ecological and genetic factors that may affect the likelihood of emergence: migration, life history of the infectious agent, host heterogeneity, and the rate and effects of mutations. We contrast different modelling approaches and indicate how details in the way we model each step of a life cycle can have important consequences on the predicted probability of evolutionary emergence. These different theoretical perspectives yield important insights into optimal surveillance and intervention strategies, which should aim for a reduction in the emergence (and re-emergence) of infectious diseases.
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