ArticlePlant physiology2013
Proteome analysis in Arabidopsis reveals shoot- and root-specific targets of cytokinin action and differential regulation of hormonal homeostasis.
Article in Plant physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.
- Hydrogen Peroxide: Its Role in Plant Biology and Crosstalk with Signalling Networks.International journal of molecular sciences · 2018Pooled it
- Gene Editing of Nicotiana benthamiana Architecture for Space-Efficient Production of Recombinant Proteins in Closed Environments.Plant biotechnology journal · 2026Article
- Effects of benzylaminopurine and gibberellic acid on growth, yield, and nutrient composition of greenhouse cultivated yellow cherry tomatoes.Scientific reports · 2025Article
- Micropropagation of Apple Cultivars 'Golden Delicious' and 'Royal Gala' in Bioreactors.Plants (Basel, Switzerland) · 2025Article
- Optimizing Growth Regulator Concentrations forPlants (Basel, Switzerland) · 2025Article
- BvHP4b gene in red beet promotes tuber enlargement and enhances resistance to Pst DC3000.BMC genomics · 2025Article
- Cytokinin negatively regulates tomato fruit ripening by influencing the ethylene pathway.Plant cell reports · 2025Article
- Cytokinins regulate spatially specific ethylene production to control root growth in Arabidopsis.Plant communications · 2024Article
- Hyperhydricity in Plant Tissue Culture.Plants (Basel, Switzerland) · 2022Review
- Glucose-6-P/phosphate translocator2 mediates the phosphoglucose-isomerase1-independent response to microbial volatiles.Plant physiology · 2022Article
- Cytokinin and abiotic stress tolerance -What has been accomplished and the way forward?Frontiers in genetics · 2022Review
- Article
- Silencing ofInternational journal of molecular sciences · 2020Article
- Article
- Barley Root Proteome and Metabolome in Response to Cytokinin and Abiotic Stimuli.Frontiers in plant science · 2020Article
- ETR1 Integrates Response to Ethylene and Cytokinins into a Single Multistep Phosphorelay Pathway to Control Root Growth.Molecular plant · 2019Article
- Root Proteomics Reveals the Effects of Wood Vinegar on Wheat Growth and Subsequent Tolerance to Drought Stress.International journal of molecular sciences · 2019Article
- The Coordination of Ethylene and Other Hormones in Primary Root Development.Frontiers in plant science · 2019Review
- Cytokinin Transporters: Multisite Players in Cytokinin Homeostasis and Signal Distribution.Frontiers in plant science · 2019Review
- Stimulation of ipt overexpression as a tool to elucidate the role of cytokinins in high temperature responses of Arabidopsis thaliana.Journal of experimental botany · 2016Article
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The plant hormones cytokinins (CKs) regulate multiple developmental and physiological processes in Arabidopsis (Arabidopsis thaliana). Responses to CKs vary in different organs and tissues (e.g. the response to CKs has been shown to be opposite in shoot and root samples). However, the tissue-specific targets of CKs and the mechanisms underlying such specificity remain largely unclear. Here, we show that the Arabidopsis proteome responds with strong tissue and time specificity to the aromatic CK 6-benzylaminopurine (BAP) and that fast posttranscriptional and/or posttranslational regulation of protein abundance is involved in the contrasting shoot and root proteome responses to BAP. We demonstrate that BAP predominantly regulates proteins involved in carbohydrate and energy metabolism in the shoot as well as protein synthesis and destination in the root. Furthermore, we found that BAP treatment affects endogenous hormonal homeostasis, again with strong tissue specificity. In the shoot, BAP up-regulates the abundance of proteins involved in abscisic acid (ABA) biosynthesis and the ABA response, whereas in the root, BAP rapidly and strongly up-regulates the majority of proteins in the ethylene biosynthetic pathway. This was further corroborated by direct measurements of hormone metabolites, showing that BAP increases ABA levels in the shoot and 1-aminocyclopropane-1-carboxylic acid, the rate-limiting precursor of ethylene biosynthesis, in the root. In support of the physiological importance of these findings, we identified the role of proteins mediating BAP-induced ethylene production, METHIONINE SYNTHASE1 and ACC OXIDASE2, in the early root growth response to BAP.
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