Evidence map›Paper›PMID 23208618›Full record

ArticleAdvanced healthcare materials2013

Core-shell hydrogel microcapsules for improved islets encapsulation.

Minglin Ma, Alan Chiu, Gaurav Sahay, Joshua C Doloff, Nimit Dholakia, Raj Thakrar, Joshua Cohen, Arturo Vegas, Delai Chen, Kaitlin M Bratlie and 5 more

Open access · greenAbstract read
In one paragraph

Article in Advanced healthcare materials, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
7.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 161 citations in OpenAlex.

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  16. Profile likelihood analysis for a stochastic model of diffusion in heterogeneous media.Proceedings. Mathematical, physical, and engineering sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Minglin MaDavid H Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.
Alan Chiu
Gaurav Sahay
Joshua C Doloff
Nimit Dholakia
Raj Thakrar
Joshua Cohen
Arturo Vegas
Delai Chen
Kaitlin M Bratlie
Tram Dang
Roger L York
Jennifer Hollister-Lock
Gordon C Weir
Daniel G Anderson
Massachusetts Institute of Technology · USBoston Children's Hospital · USJoslin Diabetes Center · USIowa State University · US

Funding

VIRUS PRODUCTION COREP30CA014051 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI Jacqueline A. Lees · 1985 to 2026
$93.9M
Understanding biocompatibility through novel in vivo imagingF32EB011580 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BRATLIE, KAITLIN M. · 2010 to 2011
$84k
NCI NIH HHS P30 CA014051NIBIB NIH HHS F32 EB011580NIBIB NIH HHS F32 EB011580-01
6 · The paper itself

Abstract

Islets microencapsulation holds great promise to treat type 1 diabetes. Currently used alginate microcapsules often have islets protruding outside capsules, leading to inadequate immuno-protection. A novel design of microcapsules with core-shell structures using a two-fluid co-axial electro-jetting is reported. Improved encapsulation and diabetes correction is achieved in a single step by simply confining the islets in the core region of the capsules.

Indexed as

Tissue ScaffoldsAlginatesAnimalsBiocompatible MaterialsCapsulesCell Culture TechniquesCells, CulturedDiabetes Mellitus, ExperimentalGlucuronic AcidHexuronic AcidsHydrogelsIslets of Langerhans TransplantationMaleMiceMice, Inbred C57BLPorosityAlginatesBiocompatible MaterialsCapsulesGlucuronic AcidHexuronic AcidsHydrogelsStreptozocin

Identifiers

PMID23208618
PMCPMC3814167
OpenAlexW2047757400

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.