Evidence map›Paper›PMID 23208524›Full record

ReviewNutrients2012

Molecular nutrition research: the modern way of performing nutritional science.

Frode Norheim, Ingrid Merethe Fange Gjelstad, Marit Hjorth, Kathrine J Vinknes, Torgrim M Langleite, Torgeir Holen, Jørgen Jensen, Knut Tomas Dalen, Anette S Karlsen, Anders Kielland and 2 more

Abstract readReview
In one paragraph

Review in Nutrients, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Nutrient Utilization, Requirements and Nutrigenomics in Sheep and Goats.Animals : an open access journal from MDPI · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Special issue: molecular nutrition and chronic diseases.Journal of Zhejiang University. Science. B · 2023
    Article
  8. Polymorphisms, diet and nutrigenomics.Journal of preventive medicine and hygiene · 2022
    Review
  9. Article
  10. A Background Search on the Potential Role ofBioMed research international · 2022
    Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Frode NorheimDepartment of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Blindern, Oslo, Norway. frode.norheim@medisin.uio.no
Ingrid Merethe Fange Gjelstad
Marit Hjorth
Kathrine J Vinknes
Torgrim M Langleite
Torgeir Holen
Jørgen Jensen
Knut Tomas Dalen
Anette S Karlsen
Anders Kielland
Arild C Rustan
Christian A Drevon

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In spite of amazing progress in food supply and nutritional science, and a striking increase in life expectancy of approximately 2.5 months per year in many countries during the previous 150 years, modern nutritional research has a great potential of still contributing to improved health for future generations, granted that the revolutions in molecular and systems technologies are applied to nutritional questions. Descriptive and mechanistic studies using state of the art epidemiology, food intake registration, genomics with single nucleotide polymorphisms (SNPs) and epigenomics, transcriptomics, proteomics, metabolomics, advanced biostatistics, imaging, calorimetry, cell biology, challenge tests (meals, exercise, etc.), and integration of all data by systems biology, will provide insight on a much higher level than today in a field we may name molecular nutrition research. To take advantage of all the new technologies scientists should develop international collaboration and gather data in large open access databases like the suggested Nutritional Phenotype database (dbNP). This collaboration will promote standardization of procedures (SOP), and provide a possibility to use collected data in future research projects. The ultimate goals of future nutritional research are to understand the detailed mechanisms of action for how nutrients/foods interact with the body and thereby enhance health and treat diet-related diseases.

Indexed as

DietNutritional SciencesResearch DesignHumansNutrigenomicsNutritional Physiological Phenomena

Identifiers

PMID23208524
PMCPMC3546614

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.