ArticleThe journal of nutrition, health & aging2012
Frailty in relation to the risk of falls, fractures, and mortality in older Chinese adults: results from the Beijing Longitudinal Study of Aging.
Article in The journal of nutrition, health & aging, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
71 citing papers in PubMed, 2 syntheses or guidelines pooled it, 127 citations in OpenAlex.
- Is frailty associated with increased concerns about falling and activity restriction in community-dwelling older adults? A systematic review.The Journal of frailty & aging · 2025Pooled it
- Screening for frailty in primary care: a systematic review of the psychometric properties of the frailty index in community-dwelling older people.BMC geriatrics · 2014Pooled it
- Frailty Change and Major Osteoporotic Fracture in the Elderly: Data from the Global Longitudinal Study of Osteoporosis in Women 3-Year Hamilton Cohort.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2016Trial
- Frailty predicts short-term incidence of future falls among British community-dwelling older people: a prospective cohort study nested within a randomised controlled trial.BMC geriatrics · 2015Trial
- Age-period-cohort decomposition and projections of the frailty index among older adults in China.Frontiers in public health · 2026Article
- Two-year evolution of frailty status and predictive factors in Chinese older adults: a national longitudinal study.BMC geriatrics · 2025Article
- Impact of social vulnerability on frailty transition among older adults in China: a national two-year cohort study.Journal of global health · 2025Article
- Excess short- and long-term mortality risk following any and hip fractures: a prospective matched cohort study using exposure density sampling.Scientific reports · 2025Article
- Low relative sit-to-stand power is associated with history of falls and fractures, prospective hospitalization, and all-cause mortality in older adults from the Toledo study for healthy aging.Journal of sport and health science · 2025Article
- Frailty as a predictor of vertebral fractures in osteoporosis: A clinical perspective.Joint diseases and related surgery · 2025Article
- Article
- Impact of frailty and prevalent fractures on the long-term prognosis of patients with cirrhosis: a retrospective study.Scientific reports · 2025Article
- Factors Associated with Frailty Transitions Using the Kihon Checklist: A 6-Year Longitudinal Study Among Japanese Residents.Clinical interventions in aging · 2025Article
- Systematic review of methods used in prediction models with recurrent event data.Diagnostic and prognostic research · 2024Article
- Bibliometric Insights into Research on Frailty and Falls.Ethiopian journal of health sciences · 2024Review
- Incorporating frailty to address the key challenges to geriatric economic evaluation.BMC geriatrics · 2024Article
- Association between disability and cognitive function in older Chinese people: a moderated mediation of social relationships and depressive symptoms.Frontiers in public health · 2024Article
- The Five Times Sit-to-Stand Test is associated with both history of falls and fear of falling among community adults aged 50 years and older.Irish journal of medical science · 2023Article
- Determining factors that maintain physical function or increase frailty using the Kihon checklist among community-dwelling older adults: a six-year longitudinal study in Agano, Japan.BMC geriatrics · 2023Article
- Multisystem physiological perspective of human frailty and its modulation by physical activity.Physiological reviews · 2023Review
11 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
Abstract
objectivesFalls are well known to be associated with adverse health outcomes, especially when complicated by fracture. Falls are more common in people who are frail and readily related to several items in the frailty phenotype. Less is known about the relationship between falls and frailty defined as deficit accumulation. Our objective was to investigate the relationship between falls, fractures, and frailty based on deficit accumulation.
designRepresentative cohort study, with 8 year follow-up.
settingThe Beijing Longitudinal Study of Aging (BLSA).
participants3,257 Chinese people aged 55+ years at baseline. MEASUREMENTS: A frailty index (FI) was constructed using 33 health deficits, but excluding falls and fractures. The rates of falls, fractures and death as a function of age and the FI were analyzed. Multivariable models evaluated the relationships between frailty and the risk of recurrent falls, fractures, and mortality adjusting for age, sex, and education. Self or informant reported fall and fracture data were verified against participants' health records.
resultsOf 3,257 participants at baseline (1992), 360 people (11.1%) reported a history of falls, and 238 (7.3%) reported fractures. By eight years, 1,155 people had died (35.3%). The FI was associated with an increased risk of recurrent falls (OR=1.54; 95% confidence interval (CI)=1.34-1.76), fractures (OR=1.07; 95% CI=0.94-1.22), and death (OR=1.50, 95% CI=1.41-1.60). The FI showed a significant effect on mortality in a multivariate Cox regression model (Hazard Rate=1.29, 95% CI=1.25-1.33). When adjusted for the FI, neither falls nor fractures were associated with mortality.
conclusionFalls and fractures were common in older Chinese adults, and associated with frailty. Only frailty was independently associated with death.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.