ReviewTechniques in coloproctology2013
The treatment of anal fistulas with biologically derived products: is innovation better than conventional surgical treatment? An update.
Review in Techniques in coloproctology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Evaluation and management of perianal abscess and anal fistula: SICCR position statement.Techniques in coloproctology · 2020Guideline
- Fistulotomy or fistulectomy and primary sphincteroplasty for anal fistula (FIPS): a systematic review.Techniques in coloproctology · 2015Pooled it
- Systematic review and meta-analysis of surgical interventions for high cryptoglandular perianal fistula.International journal of colorectal disease · 2015Pooled it
- Comparison of incision and drainage procedure with drainage and ligation of the intersphincteric fistula tract in the treatment of deep perianal abscess.Scientific reports · 2026Article
- Risk factors for postoperative urinary retention in patients underwent surgery for benign anorectal diseases: a nested case-control study.BMC anesthesiology · 2024Article
- Evaluation surgical strategies in perianal fistulas treatment: Efficacy draining seton compared to other surgical approaches; a case-control study.Health science reports · 2024Article
- Surgery for anal fistulae: state of the art.International journal of colorectal disease · 2021Review
- Anal Fistula Laser Closure: the length of fistula is the Achilles' heel.Techniques in coloproctology · 2018Observational
- Evaluation and management of perianal abscess and anal fistula: a consensus statement developed by the Italian Society of Colorectal Surgery (SICCR).Techniques in coloproctology · 2015Review
- Treatment of Fistula-In-Ano with Fistula Plug - a Review Under Special Consideration of the Technique.Frontiers in surgery · 2015Review
- Biomaterials in the treatment of anal fistula: hope or hype?Clinics in colon and rectal surgery · 2014Review
- The role of loose seton in the management of anal fistula: a multicenter study of 200 patients.Techniques in coloproctology · 2014Article
- Modified plug repair with limited sphincter sparing fistulectomy in the treatment of complex anal fistulas.Frontiers in surgery · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
New technical approaches involving biologically derived products have been applied in the treatment for anal fistulas in order to avoid the risk of fecal incontinence. The aim of this review was to evaluate the scientific evidence present in the literature regarding these techniques. Trials comparing surgery (fistulotomy, advancement mucosal flap closure and placement of seton) versus fibrin glue, fistula plug or acellular dermal matrix were considered. In fibrin glue versus traditional surgical treatment the healing rate was higher in the surgery group, and the recurrence rate was lower in the traditional surgery group, but these results were not statistically relevant. In acellular dermal matrix (ADM) versus traditional surgical treatment the recurrence rate of fistulas was significantly lower in the ADM group, but non-significant differences were recorded in incontinence and anal deformity. Our review shows that there are no significant advantages of the new techniques involving biologically derived products. Further randomized controlled trials are needed.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.