SynthesisNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2013
Chronic smoking and brain gray matter changes: evidence from meta-analysis of voxel-based morphometry studies.
Synthesis in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 4 of them syntheses that pooled it.
What it found
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Who cites it
47 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Voxel-wise meta-analysis of structural changes in gray matter of Parkinson's disease patients with mild cognitive impairment.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2020Pooled it
- Is psychosis a multisystem disorder? A meta-review of central nervous system, immune, cardiometabolic, and endocrine alterations in first-episode psychosis and perspective on potential models.Molecular psychiatry · 2019Pooled it
- Chronic cigarette smoking is linked with structural alterations in brain regions showing acute nicotinic drug-induced functional modulations.Behavioral and brain functions : BBF · 2016Pooled it
- Identification of a common neurobiological substrate for mental illness.JAMA psychiatry · 2015Pooled it
- Bidirectional genetic and phenotypic links between smoking and striatal iron content involving dopaminergic and inflammatory pathways.Addiction (Abingdon, England) · 2026Article
- Network localization of gray matter alterations in chronic smokers using the normative functional connectome.Frontiers in public health · 2026Article
- Sex-dominant differences in resting-state EEG microstates among young adults at risk of smartphone addiction.Frontiers in human neuroscience · 2026Article
- Microstructural Brain Correlates of Inter-individual Differences in Respiratory Interoception.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Tobacco Smoking and Gray Matter Volume in Individuals at Clinical High Risk for Psychosis: A Longitudinal Magnetic Resonance Imaging Study.Biological psychiatry global open science · 2025Article
- Neuroimaging Biomarkers in Addiction.medRxiv : the preprint server for health sciences · 2024Article
- Longstanding smoking associated with frontal brain lobe atrophy: a 32-year follow-up study in women.BMJ open · 2023Article
- Associations between right inferior frontal gyrus morphometry and inhibitory control in individuals with nicotine dependence.Drug and alcohol dependence · 2023Article
- Connectome-based predictive modeling of smoking severity using individualized structural covariance network in smokers.Frontiers in neuroscience · 2023Article
- Assessment of brain connectome alterations in male chronic smokers using structural and generalized q-sampling MRI.Brain imaging and behavior · 2022Article
- Gray matter volumes of the insula and anterior cingulate cortex and their dysfunctional roles in cigarette smoking.Addiction neuroscience · 2022Article
- Effect of alcohol, tobacco, and cannabis co-use on gray matter volume in heavy drinkers.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2021Article
- Association between functional brain alterations and neuropsychological scales in male chronic smokers using resting-state fMRI.Psychopharmacology · 2021Article
- The modulating impact of cigarette smoking on brain structure in panic disorder: a voxel-based morphometry study.Social cognitive and affective neuroscience · 2020Article
- Contribution of normal aging to brain atrophy in MS.Neurology(R) neuroimmunology & neuroinflammation · 2019Article
- Neuroimaging reward, craving, learning, and cognitive control in substance use disorders: review and implications for treatment.The British journal of radiology · 2019Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Structural neuroimaging studies on chronic smokers using voxel-based morphometry (VBM) had provided cumulative evidence of gray matter (GM) changes relative to nonsmokers. However, not all the studies reported entirely consistent findings. Here, we aimed at identifying consistent GM anomalies in chronic smokers by performing a meta-analysis, and a systematic search of VBM studies on chronic smokers and nonsmokers published in PubMed and Embase database from 2000 to April 2012. Meta-analysis was performed using a newly improved voxel-based meta-analytic tool, namely effect size signed differential mapping, to quantitatively explore the GM abnormalities between chronic smokers and nonsmokers. A total of 7 eligible VBM studies involving 213 chronic smokers and 205 nonsmokers met the inclusion criteria. A considerable regional GM volume decrease was detected in the anterior cingulate cortex (ACC) (BA 24) extending to BA32 in chronic smokers. The findings remain largely unchanged in the entire brain jackknife sensitivity analyses. The results of the present meta-analysis provide evidence of GM changes in ACC in chronic smokers which may be an important potential therapeutic neuro-target for nicotine dependence.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.