Evidence map›Paper›PMID 23206376›Full record

Trial reportDrug and alcohol dependence2013

Does Alcoholics Anonymous work differently for men and women? A moderated multiple-mediation analysis in a large clinical sample.

John F Kelly, Bettina B Hoeppner

Abstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Drug and alcohol dependence, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Women with alcohol dependence: A randomized trial of couple versus individual plus couple therapy.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2016
    Trial
  4. Trial
  5. A meta-review of the evidence on addiction recovery mutual help organizations.Alcohol and alcoholism (Oxford, Oxfordshire) · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Sex and Gender Effects in Recovery From Alcohol Use Disorder.Alcohol research : current reviews · 2020
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Lifetime Alcoholics Anonymous attendance as a predictor of spiritual gains in the Relapse Replication and Extension Project (RREP).Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2017
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

John F KellyCenter for Addiction Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, United States. jkelly11@partners.org
Bettina B Hoeppner

Funding

Dynamic Processes of Smoking CessationK01DA027097 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI HOEPPNER, BETTINA B. · 2010 to 2014
$834k
Mechanisms and Moderators of Behavior Change in Alcoholics AnonymousR21AA016762 · NIAAA · MASSACHUSETTS GENERAL HOSPITAL · PI KELLY, JOHN F. · 2007 to 2008
$466k
NIAAA NIH HHS R21 AA016762NIDA NIH HHS K01 DA027097NIDA NIH HHS L30 DA025511
6 · The paper itself

Abstract

backgroundAlcoholics Anonymous (AA) began as a male organization, but about one third is now female. Studies have found that women participate at least as much as men and benefit equally from AA, but it is unclear whether women benefit from AA in the same or different ways as men. This study tested whether gender moderated the mechanisms through which AA aids recovery.

methodsA cohort study of alcohol dependent adults (N=1726; 24% female; Project MATCH) was assessed on AA attendance during treatment; with mediators at 9 months; outcomes (Percent Days Abstinent [PDA] and Drinks per Drinking Day [DDD]) at 15 months. Multiple mediator models tested whether purported mechanisms (i.e., self-efficacy, depression, social networks, spirituality/religiosity) explained AA's effects differently for men and women controlling for baseline values, mediators, treatment, and other confounders.

resultsFor PDA, the proportion of AA's effect accounted for by the mediators was similar for men (53%) and women (49%). Both men and women were found to benefit from changes in social factors but these mechanisms were more important among men. For DDD, the mediators accounted for 70% of the effect of AA for men and 41% for women. Again, men benefitted mostly from social changes. Independent of AA's effects, negative affect self-efficacy was shown to have a strong relationship to outcome for women but not men.

conclusionsThe recovery benefits derived from AA differ in nature and magnitude between men and women and may reflect differing needs based on recovery challenges related to gender-based social roles and drinking contexts.

Indexed as

Alcoholics AnonymousAdultAlcoholismCognitive Behavioral TherapyCohort StudiesFemaleHumansMaleMiddle AgedMotivational InterviewingSex FactorsTemperanceTreatment Outcome

Identifiers

PMID23206376
PMCPMC3596430

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.