Evidence map›Paper›PMID 23205755›Full record

SynthesisJournal of clinical hypertension (Greenwich, Conn.)2012

A systematic review of patient self-reported barriers of adherence to antihypertensive medications using the world health organization multidimensional adherence model.

Suliman A AlGhurair, Christine A Hughes, Scot H Simpson, Lisa M Guirguis

Registry-linked trialAbstract readSystematic Review
In one paragraph

Synthesis in Journal of clinical hypertension (Greenwich, Conn.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07397260 (Effects of Manually Recorded or Automatically Transmitted Home Blood Pressures With or Without Automated Patient Feedback on Hypertension Care), which is not on this map. Cited by 84 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07397260 naenrolling by invitationnot on this mapstarted 2026, after this paper: background citation

Effects of Manually Recorded or Automatically Transmitted Home Blood Pressures With or Without Automated Patient Feedback on Hypertension Care

TypeinterventionalSponsorNorthwestern UniversityRan2026 to 2028Enrolled1,304ConditionsHypertension (HTN)ArmsSelf report of home measured blood pressure via patient EHR portal, Automated feedback about home blood pressure results, Automated Transmission of Remotely Measured Blood Pressure
3 · Its place in the literature

Who cites it

84 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Pooled it
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  9. Trial
  10. Reinforcing adherence to antihypertensive medications.Journal of clinical hypertension (Greenwich, Conn.) · 2015
    Trial
  11. Trial
  12. Article
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  18. Do Patient Preferences and Treatment Beliefs Explain Patterns of Antihypertensive Medication Nonadherence? A Discrete Choice Experiment.Medical decision making : an international journal of the Society for Medical Decision Making · 2026
    Article
  19. Sleep apnea in individuals with spinal cord injury.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  20. Article

24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Suliman A AlGhurairFaculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.
Christine A Hughes
Scot H Simpson
Lisa M Guirguis

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple barriers can influence adherence to antihypertensive medications. The aim of this systematic review was to determine what adherence barriers were included in each instrument and to describe the psychometric properties of the identified surveys. Barriers were characterized using the World Health Organization (WHO) Multidimensional Adherence Model with patient, condition, therapy, socioeconomic, and health care system/team-related barriers. Five databases (Medline, Embase, Health and Psychological Instruments, CINHAL, and International Pharmaceutical Abstracts [IPA]) were searched from 1980 to September 2011. Our search identified 1712 citations; 74 articles met inclusion criteria and 51 unique surveys were identified. The Morisky Medication Adherence Scale was the most commonly used survey. Only 20 surveys (39%) have established reliability and validity evidence. According to the WHO Adherence Model domains, patient-related barriers were most commonly addressed, while condition, therapy, and socioeconomic barriers were underrepresented. The complexity of adherence behavior requires robust self-report measurements and the inclusion of barriers relevant to each unique patient population and intervention.

Indexed as

Antihypertensive AgentsConsumer Health InformationDrug MonitoringMedication AdherenceSelf ReportHealth LiteracyHumansHypertensionReproducibility of ResultsSocioeconomic FactorsWorld Health OrganizationAntihypertensive Agents

Identifiers

PMID23205755
PMCPMC8108877

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.