ArticleJournal of clinical and experimental neuropsychology2013
AD pathology and cerebral infarctions are associated with memory and executive functioning one and five years before death.
Article in Journal of clinical and experimental neuropsychology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 13 citations in OpenAlex.
- Vitamin D and Vitamin K Concentrations in Human Brain Tissue Are Influenced by Freezer Storage Time: The Memory and Aging Project.The Journal of nutrition · 2021Article
- Latent Cognitive Class at Enrollment Predicts Future Cognitive Trajectories of Decline in a Community Sample of Older Adults.Journal of Alzheimer's disease : JAD · 2021Article
- Neuropsychological latent classes at enrollment and postmortem neuropathology.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2019Article
- A new era for dementia epidemiology: Alzheimer's disease, hardening of arteries, or just old age?European journal of epidemiology · 2018Review
- Religious Orders Study and Rush Memory and Aging Project.Journal of Alzheimer's disease : JAD · 2018Review
- Disentangling the effects of age and APOE on neuropathology and late life cognitive decline.Neurobiology of aging · 2014Article
- Biomarker modelling of early molecular changes in Alzheimer's disease.Molecular diagnosis & therapy · 2014Review
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 1 country.
Funding
Abstract
We provide rigorous psychometric evidence for distinct patterns of cognitive impairment for Alzheimer's disease (AD) and cerebral infarctions using 440 participants from the Religious Order Study. Latent variable models were used to decompose the effects of AD pathology and cerebral infarctions assessed at autopsy on overall cognition and specific neuropsychological tests at one and five years prior to death. Results support clinical and univariate psychometric analyses that memory impairment is more pronounced in AD, and executive impairment is more pronounced in the presence of cerebral infarctions. These specific effects are subtle relative to the stronger associations of both AD neuropathology and cerebral infarctions with overall levels of cognitive impairment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.