Evidence map›Paper›PMID 23205295›Full record

ArticleJournal of thoracic disease2012

Breast cancer manifested by hematologic disorders.

Takashi Ishikawa, Daisuke Shimizu, Ayako Kito, Ikuko Ota, Takeshi Sasaki, Mikiko Tanabe, Akimitsu Yamada, Hitoshi Arioka, Satoru Shimizu, Junichi Wakasugi and 4 more

Abstract readCase Reports
In one paragraph

Article in Journal of thoracic disease, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trastuzumab plus capecitabine vs. lapatinib plus capecitabine in patients with trastuzumab resistance and taxane-pretreated metastatic breast cancer.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2013
    Trial
  2. Article
  3. Article
  4. PARP inhibitor reduces proliferation and increases apoptosis in breast cancer cells.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2014
    Article
  5. QM-FISH analysis of the genes involved in the G1/S checkpoint signaling pathway in triple-negative breast cancer.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014
    Article
  6. Clinical pathological characteristics and prognostic analysis of diabetic women with luminal subtype breast cancer.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014
    Article
  7. Effects of ARHI on breast cancer cell biological behavior regulated by microRNA-221.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2013
    Article
  8. Article
  9. Expression and regulatory function of miRNA-182 in triple-negative breast cancer cells through its targeting of profilin 1.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2013
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Takashi IshikawaDepartment of Breast and Thyroid Surgery Yokohama City University Medical Center, 4-57 Urafune-cho, Minami-ku, Yokohama 232-0024, Japan;
Daisuke Shimizu
Ayako Kito
Ikuko Ota
Takeshi Sasaki
Mikiko Tanabe
Akimitsu Yamada
Hitoshi Arioka
Satoru Shimizu
Junichi Wakasugi
Ryutaro Mori
Takashi Chishima
Yasushi Ichikawa
Itaru Endo
Yokohama City University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer is the most common type of cancer in women. However, it is very rarely manifested as hematologic disorders. A 35-year-old woman was admitted because of disseminated intravascular coagulation. Examinations revealed the presence of breast cancer in her left breast; therefore, paclitaxel was administered weekly. Although disseminated intravascular coagulation was controlled, pulmonary dysfunction due to lymphangitis carcinomatosa suddenly occurred 10 weeks after treatment. Pulmonary dysfunction was effectively treated with epirubicin and cyclophosphamide. Twenty-three weeks after treatment, the patient developed liver dysfunction accompanied with jaundice due to progressive metastatic lesions in the liver; liver dysfunction improved after the administration of vinorelbine. Subsequently, because of the recurrence of pulmonary dysfunction, rechallenge with epirubicin and cyclophosphamide was performed and was effective; however, this therapy was discontinued because of its adverse effects. She expired of liver failure 33 weeks after the occurrence of disseminated intravascular coagulation. Metastatic tumors in the bone marrow, lung, and liver showed different sensitivities to different anti-cancer agents. We report a case of breast cancer manifested by hematologic disorders which was treated by a sequential chemotherapy.

Indexed as

Breast cancerdisseminated intravascular coagulationmultiple organ metastases

Identifiers

PMID23205295
PMCPMC3506789
OpenAlexW2153322939

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.