ArticleCurrent genomics2012
From lizard to snake; behind the evolution of an extreme body plan.
Article in Current genomics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- Reflections on Model Species in Evolutionary Developmental Biology.Results and problems in cell differentiation · 2026Review
- Evolvability in vertebrate segmentation.Seminars in cell & developmental biology · 2025Review
- Development necessitates evolutionarily conserved factors.Scientific reports · 2025Article
- Conservation of rib skeleton regionalization in the homoplastic evolution of the snake-like body form in squamates.Proceedings. Biological sciences · 2024Article
- Patterns of girdle shape and their correlates in Australian limb-reduced skinks.Proceedings. Biological sciences · 2024Article
- Repatterning of mammalian backbone regionalization in cetaceans.Nature communications · 2024Article
- Integrated Analysis of Transcriptome Expression Profiles Reveals miRNA-326-NKX3.2-Regulated Porcine Chondrocyte Differentiation.International journal of molecular sciences · 2023Article
- Repeated evolution of similar phenotypes: Integrating comparative methods with developmental pathways.Genetics and molecular biology · 2023Article
- Unique bone microanatomy reveals ancestry of subterranean specializations in mammals.Evolution letters · 2022Article
- Characterization of the bacterial microbiota in different gut and oral compartments of splendid japalure (Japalura sensu lato).BMC veterinary research · 2022Article
- Variation in vertebrae shape across small-bodied newts reveals functional and developmental constraints acting upon the trunk region.Journal of anatomy · 2022Article
- Single-cell RNA Sequencing Reveals Thoracolumbar Vertebra Heterogeneity and Rib-genesis in Pigs.Genomics, proteomics & bioinformatics · 2021Article
- Article
- Captivity affects diversity, abundance, and functional pathways of gut microbiota in the northern grass lizard Takydromus septentrionalis.MicrobiologyOpen · 2020Article
- The iliosacral joint in lizards: an osteological and histological analysis.Journal of anatomy · 2020Article
- Evolutionary lability inEvolution letters · 2019Article
- The skeletal ontogeny of Astatotilapia burtoni - a direct-developing model system for the evolution and development of the teleost body plan.BMC developmental biology · 2018Article
- Hox genes and evolution.F1000Research · 2016Review
- Tetrapod axial evolution and developmental constraints; Empirical underpinning by a mouse model.Mechanisms of development · 2015Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The elongated, snake-like skeleton, as it has convergently evolved in numerous reptilian and amphibian lineages, is from a developmental biologist's point of view amongst the most fascinating anatomical peculiarities in the animal kingdom. This type of body plan is characterized by a greatly increased number of vertebrae, a reduction of skeletal regionalization along the primary body axis and loss of the limbs. Recent studies conducted on both mouse and snakes now hint at how changes inside the gene regulatory circuitries of the Hox genes and the somitogenesis clock likely underlie these striking departures from standard tetrapod morphology, suggesting scenarios by which snakes and other elongated species may have evolved from more ordinarily bodied ancestors.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.