Evidence map›Paper›PMID 23204872›Full record

ArticleInternational journal of women's health2012

Vaginal rings for delivery of HIV microbicides.

R Karl Malcolm, Susan M Fetherston, Clare F McCoy, Peter Boyd, Ian Major

Abstract read
In one paragraph

Article in International journal of women's health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Use of simulated vaginal and menstrual fluids to modelInternational journal of pharmaceutics: X · 2021
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Vaginal drug delivery for the localised treatment of cervical cancer.Drug delivery and translational research · 2017
    Review
  13. Long-Acting Antiretrovirals: Where Are We now?Current HIV/AIDS reports · 2017
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

R Karl MalcolmSchool of Pharmacy, Queen's University Belfast, Belfast, UK.
Susan M Fetherston
Clare F McCoy
Peter Boyd
Ian Major

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Following the successful development of long-acting steroid-releasing vaginal ring devices for the treatment of menopausal symptoms and contraception, there is now considerable interest in applying similar devices to the controlled release of microbicides against HIV. In this review article, the vaginal ring concept is first considered within the wider context of the early advances in controlled-release technology, before describing the various types of ring device available today. The remainder of the article highlights the key developments in HIV microbicide-releasing vaginal rings, with a particular focus on the dapivirine ring that is presently in late-stage clinical testing.

Indexed as

antiretroviralcontrolled releasedapivirineSILCS diaphragmsilicone elastomersustained releasethermoplastic

Identifiers

PMID23204872
PMCPMC3508658

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.