Evidence map›Paper›PMID 23204365›Full record

ReviewMicrobiology and molecular biology reviews : MMBR2012

Type IV pilin proteins: versatile molecular modules.

Carmen L Giltner, Ylan Nguyen, Lori L Burrows

Abstract readReview
In one paragraph

Review in Microbiology and molecular biology reviews : MMBR, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 259 papers.

0numbers the graph read from it
0cells of the map it votes in
259citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

259 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Defining the role ofJournal of bacteriology · 2026
    Article
  5. Expression of soluble Type IV Minor Pilins and isolation of abioRxiv : the preprint server for biology · 2026
    Article
  6. Type IV pilin regulation: a transcriptional overview.Critical reviews in microbiology · 2026
    Review
  7. Article
  8. Review
  9. Article
  10. Deciphering the genomic landscape of novelFrontiers in microbiology · 2026
    Article
  11. Article
  12. International journal of molecular sciences · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Separation ofmBio · 2025
    Article
  17. Stimulation of themBio · 2025
    Article
  18. Article
  19. Integrative Structure and Function of thebioRxiv : the preprint server for biology · 2025
    Article
  20. Article

199 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Carmen L GiltnerThe Department of Biochemistry and Biomedical Sciences and the Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada.
Ylan Nguyen
Lori L Burrows

Funding

Canadian Institutes of Health Research MOP 86639
6 · The paper itself

Abstract

Type IV pili (T4P) are multifunctional protein fibers produced on the surfaces of a wide variety of bacteria and archaea. The major subunit of T4P is the type IV pilin, and structurally related proteins are found as components of the type II secretion (T2S) system, where they are called pseudopilins; of DNA uptake/competence systems in both Gram-negative and Gram-positive species; and of flagella, pili, and sugar-binding systems in the archaea. This broad distribution of a single protein family implies both a common evolutionary origin and a highly adaptable functional plan. The type IV pilin is a remarkably versatile architectural module that has been adopted widely for a variety of functions, including motility, attachment to chemically diverse surfaces, electrical conductance, acquisition of DNA, and secretion of a broad range of structurally distinct protein substrates. In this review, we consider recent advances in this research area, from structural revelations to insights into diversity, posttranslational modifications, regulation, and function.

Indexed as

Bacterial Physiological PhenomenaFimbriae ProteinsHost-Pathogen InteractionsProtein SubunitsBiofilmsConjugation, GeneticFimbriae, BacterialGenetic VariationPili, SexProtein Structure, SecondarySignal TransductionTranscription, GeneticFimbriae ProteinsProtein Subunits

Identifiers

PMID23204365
PMCPMC3510520

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.