Evidence map›Paper›PMID 23203986›Full record

ArticleNucleic acids research2013

Genome3D: a UK collaborative project to annotate genomic sequences with predicted 3D structures based on SCOP and CATH domains.

Tony E Lewis, Ian Sillitoe, Antonina Andreeva, Tom L Blundell, Daniel W A Buchan, Cyrus Chothia, Alison Cuff, Jose M Dana, Ioannis Filippis, Julian Gough and 14 more

Abstract read
In one paragraph

Article in Nucleic acids research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Protein domain identification methods and online resources.Computational and structural biotechnology journal · 2021
    Review
  5. Article
  6. Molecular replacement using structure predictions from databases.Acta crystallographica. Section D, Structural biology · 2019
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Guidelines for the successful generation of protein-ligand complex crystals.Acta crystallographica. Section D, Structural biology · 2017
    Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. CHOPIN: a web resource for the structural and functional proteome of Mycobacterium tuberculosis.Database : the journal of biological databases and curation · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Tony E LewisInstitute of Structural and Molecular Biology, UCL, 636 Darwin Building, Gower Street, London, WC1E 6BT, UK.
Ian Sillitoe
Antonina Andreeva
Tom L Blundell
Daniel W A Buchan
Cyrus Chothia
Alison Cuff
Jose M Dana
Ioannis Filippis
Julian Gough
Sarah Hunter
David T Jones
Lawrence A Kelley
Gerard J Kleywegt
Federico Minneci
Alex Mitchell
Alexey G Murzin
Bernardo Ochoa-Montaño
Owen J L Rackham
James Smith
Michael J E Sternberg
Sameer Velankar
Corin Yeats
Christine Orengo

Funding

Biotechnology and Biological Sciences Research CouncilMedical Research Council MC_U105192716Wellcome Trust
6 · The paper itself

Abstract

Genome3D, available at http://www.genome3d.eu, is a new collaborative project that integrates UK-based structural resources to provide a unique perspective on sequence-structure-function relationships. Leading structure prediction resources (DomSerf, FUGUE, Gene3D, pDomTHREADER, Phyre and SUPERFAMILY) provide annotations for UniProt sequences to indicate the locations of structural domains (structural annotations) and their 3D structures (structural models). Structural annotations and 3D model predictions are currently available for three model genomes (Homo sapiens, E. coli and baker's yeast), and the project will extend to other genomes in the near future. As these resources exploit different strategies for predicting structures, the main aim of Genome3D is to enable comparisons between all the resources so that biologists can see where predictions agree and are therefore more trusted. Furthermore, as these methods differ in whether they build their predictions using CATH or SCOP, Genome3D also contains the first official mapping between these two databases. This has identified pairs of similar superfamilies from the two resources at various degrees of consensus (532 bronze pairs, 527 silver pairs and 370 gold pairs).

Indexed as

Databases, ProteinProtein Structure, TertiaryGenomicsHumansInternetMolecular Sequence AnnotationProteinsSoftwareProteins

Identifiers

PMID23203986
PMCPMC3531217

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.