ArticleNucleic acids research2013
New functional families (FunFams) in CATH to improve the mapping of conserved functional sites to 3D structures.
Article in Nucleic acids research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 118 papers.
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Who cites it
118 citing papers in PubMed.
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- Contrastive learning on protein embeddings enlightens midnight zone.NAR genomics and bioinformatics · 2022Article
- Clustering FunFams using sequence embeddings improves EC purity.Bioinformatics (Oxford, England) · 2021Article
- SARS-CoV-2 structural coverage map reveals viral protein assembly, mimicry, and hijacking mechanisms.Molecular systems biology · 2021Article
- Ancient Antibiotics, Ancient Resistance.EcoSal Plus · 2021Review
- The ranging of amino acids substitution matrices of various types in accordance with the alignment accuracy criterion.BMC bioinformatics · 2020Article
- Electrostatic Interactions Govern Extreme Nascent Protein Ejection Times from Ribosomes and Can Delay Ribosome Recycling.Journal of the American Chemical Society · 2020Article
- FunFam protein families improve residue level molecular function prediction.BMC bioinformatics · 2019Article
- Environmental conditions shape the nature of a minimal bacterial genome.Nature communications · 2019Article
- Networks of electrostatic and hydrophobic interactions modulate the complex folding free energy surface of a designed βα protein.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Structure and Ligands Interactions ofBiomolecules · 2019Article
- CATH: expanding the horizons of structure-based functional annotations for genome sequences.Nucleic acids research · 2019Article
- Functional Prediction of Hypothetical Proteins from Shigella flexneri and Validation of the Predicted Models by Using ROC Curve Analysis.Genomics & informatics · 2018Article
- Analyzing protein topology based on Laguerre tessellation of a pore-traversing water network.Scientific reports · 2018Article
- The OncoPPi Portal: an integrative resource to explore and prioritize protein-protein interactions for cancer target discovery.Bioinformatics (Oxford, England) · 2018Article
- Is the hydrophobic core a universal structural element in proteins?Journal of molecular modeling · 2017Article
58 more citing papers are in PubMed but not listed here.
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13 authors.
Funding
Abstract
CATH version 3.5 (Class, Architecture, Topology, Homology, available at http://www.cathdb.info/) contains 173 536 domains, 2626 homologous superfamilies and 1313 fold groups. When focusing on structural genomics (SG) structures, we observe that the number of new folds for CATH v3.5 is slightly less than for previous releases, and this observation suggests that we may now know the majority of folds that are easily accessible to structure determination. We have improved the accuracy of our functional family (FunFams) sub-classification method and the CATH sequence domain search facility has been extended to provide FunFam annotations for each domain. The CATH website has been redesigned. We have improved the display of functional data and of conserved sequence features associated with FunFams within each CATH superfamily.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.