SynthesisInternational journal of molecular sciences2012
ABO blood group system and gastric cancer: a case-control study and meta-analysis.
Synthesis in International journal of molecular sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 3 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
57 citing papers in PubMed, 3 syntheses or guidelines pooled it, 140 citations in OpenAlex.
- ABO and Rhesus blood groups and multiple health outcomes: an umbrella review of systematic reviews with meta-analyses of observational studies.BMC medicine · 2024Pooled it
- Risk factors for gastric cancer: A comprehensive analysis of observational studies.Frontiers in public health · 2022Pooled it
- Blood groups A and AB are associated with increased gastric cancer risk: evidence from a large genetic study and systematic review.BMC cancer · 2019Pooled it
- Association of ABO and Rh blood groups with clinicopathological features and lymph node involvement in surgically treated thyroid malignancies: a retrospective single-center study.BMC endocrine disorders · 2026Article
- Pediatric ABO blood groups and disease distribution: a retrospective analysis.Translational pediatrics · 2026Article
- ABO gene polymorphisms: a molecular bridge linking disease susceptibility to therapeutic outcomes.Frontiers in medicine · 2026Review
- Clinical and Histopathological Correlations With Blood Groups in Patients With Gastric Cancer.Cureus · 2025Article
- Association of blood group types and clinico-pathological features of gynecological cancers (GCs).BMC cancer · 2025Article
- Retrospective evaluation of correlation of ABO blood groups among patients with head and neck cancer.Bioinformation · 2025Article
- The relation between ABO blood groups and clinicopathologic characteristics of the patients with gastric adenocarcinomas.Turkish journal of surgery · 2024Article
- Construction and Validation of a Gastric Cancer Diagnostic Model based on Blood Groups and Tumor Markers.Journal of Cancer · 2024Article
- Association between ABO blood groups and hematological myeloid neoplasms in adolescents and adults.Frontiers in medicine · 2024Article
- Environmental and Genetic Risk Factors for Gastric Cancer.Cancer treatment and research · 2024Review
- An Overview of Selected Bacterial Infections in Cancer, Their Virulence Factors, and Some Aspects of Infection Management.Biology · 2023Review
- An Observational Study to Analyse the Association of the ABO and Rh Blood Group Systems With Bronchial Asthma.Cureus · 2023Article
- Non-A Blood Type Is a Risk Factor for Poor Cardio-Cerebrovascular Outcomes in Patients Undergoing Dialysis.Biomedicines · 2023Article
- Article
- Radiotherapy delays malignant transformation and prolongs survival in patients with IDH-mutant gliomas.Cancer biology & medicine · 2022Article
- Lack of association between feline AB blood groups and retroviral status: a multicenter, multicountry study.Journal of feline medicine and surgery · 2022Article
- Environmental and genetic risk factors for gastric cancer.Journal of surgical oncology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study focuses on the association between the ABO blood group system and the risk of gastric cancer or Helicobacter pylori infection. The data for the ABO blood group was collected from 1045 cases of gastric cancer, whereby the patient underwent a gastrectomy in Ruijin Hospital, Shanghai. The information on the ABO blood group from 53,026 healthy blood donors was enrolled as control. We searched the Pubmed database on the relationship between ABO blood groups and gastric cancer risk for meta-analysis. In our case-control study, the risk of gastric cancer in blood group A was significantly higher than that in non-A groups (O, B and AB) (odd ratio, OR1.34; 95% confidential interval, CI 1.25-1.44). Compared with non-O groups (A, B and AB), individuals with blood group O demonstrated a reduced risk of gastric cancer (OR = 0.80; 95% CI 0.72-0.88). The proportion of H. pylori infection in blood group A individuals was significantly higher than that in non-A blood groups (OR = 1.42; 95% CI 1.05-1.93). We further combined our data with the published data of others, and crossreferenced the risk of gastric cancer with the blood type, finding consistent evidence that gastric cancer risk in the blood A group was higher than that in the non-A groups (OR = 1.11; 95% CI 1.07-1.15), and that blood type O individuals were consistently shown gastric cancer risk reduction (OR = 0.91; 95% CI 0.89-0.94). Our study concluded that there was a slightly increased risk of gastric cancer in blood group A individuals, and people with blood type A are more prone to be infected by H. pylori than other ABO blood type individuals, whereas, a slightly decreased risk of gastric cancer was identified in blood type O individuals.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.