Evidence map›Paper›PMID 23202908›Full record

ReviewInternational journal of molecular sciences2012

Implication of posttranslational histone modifications in nucleotide excision repair.

Shisheng Li

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Epigenetic Regulation of Nucleotide Excision Repair.Frontiers in cell and developmental biology · 2022
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. CREBBP and p300 lysine acetyl transferases in the DNA damage response.Cellular and molecular life sciences : CMLS · 2018
    Review
  10. Article
  11. Article
  12. Dynamic maps of UV damage formation and repair for the human genome.Proceedings of the National Academy of Sciences of the United States of America · 2017
    Article
  13. Article
  14. The Role of Gammaherpesviruses in Cancer Pathogenesis.Pathogens (Basel, Switzerland) · 2016
    Review
  15. Article
  16. Article
  17. Article
  18. Epigenetic regulation of persistent pain.Translational research : the journal of laboratory and clinical medicine · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Shisheng LiDepartment of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803, USA. shli@vetmed.lsu.edu.
Louisiana State University · US

Funding

DNA damage and repair in human melanocytes: relation to melanomagenesis mutationsR15CA164862 · NCI · LOUISIANA STATE UNIV A&M COL BATON ROUGE · PI LI, SHISHENG · 2012 to 2018
$464k
High-throughput high-resolution mapping of DNA damage and repair in human cells.R03ES020557 · NIEHS · LOUISIANA STATE UNIV A&M COL BATON ROUGE · PI LI, SHISHENG · 2012 to 2013
$147k
Intramural NIH HHSNCI NIH HHS R15 CA164862NCI NIH HHS R15CA164862NIEHS NIH HHS R03 ES020557NIEHS NIH HHS R03ES020557
6 · The paper itself

Abstract

Histones are highly alkaline proteins that package and order the DNA into chromatin in eukaryotic cells. Nucleotide excision repair (NER) is a conserved multistep reaction that removes a wide range of generally bulky and/or helix-distorting DNA lesions. Although the core biochemical mechanism of NER is relatively well known, how cells detect and repair lesions in diverse chromatin environments is still under intensive research. As with all DNA-related processes, the NER machinery must deal with the presence of organized chromatin and the physical obstacles it presents. A huge catalogue of posttranslational histone modifications has been documented. Although a comprehensive understanding of most of these modifications is still lacking, they are believed to be important regulatory elements for many biological processes, including DNA replication and repair, transcription and cell cycle control. Some of these modifications, including acetylation, methylation, phosphorylation and ubiquitination on the four core histones (H2A, H2B, H3 and H4) or the histone H2A variant H2AX, have been found to be implicated in different stages of the NER process. This review will summarize our recent understanding in this area.

Indexed as

DNA RepairChromatinHistone AcetyltransferasesHistonesHumansp300-CBP Transcription FactorsProtein Processing, Post-TranslationalChromatinHistone AcetyltransferasesHistonesp300-CBP Transcription Factors

Identifiers

PMID23202908
PMCPMC3497282
OpenAlexW1974535994

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.