Evidence map›Paper›PMID 23202530›Full record

ReviewNature reviews. Microbiology2013

The Bacillus subtilis endospore: assembly and functions of the multilayered coat.

Peter T McKenney, Adam Driks, Patrick Eichenberger

Open access · bronzeAbstract readReview
In one paragraph

Review in Nature reviews. Microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 282 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
282citing papers in PubMed, 1 pooled it
24.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

282 citing papers in PubMed, 1 synthesis or guideline pooled it, 625 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. MclX modulates the process of mother cell lysis by SpoIIID inApplied and environmental microbiology · 2026
    Article
  5. A lipid cue drives the subcellular localization of a self-inserting bacterial transmembrane protein.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Review
  7. Article
  8. Review
  9. Expression of theApplied and environmental microbiology · 2026
    Article
  10. Article
  11. New insights into the structure-based mechanism ofApplied and environmental microbiology · 2026
    Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review

222 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Peter T McKenneyCenter for Genomics and Systems Biology, Department of Biology, New York University, New York, New York 10003, USA.
Adam Driks
Patrick Eichenberger
Loyola University Chicago · USNew York Genome Center · USNew York University · US

Funding

A novel anti-spore nasal vaccine for protection from anthraxR01AI093493 · NIAID · LOYOLA UNIVERSITY CHICAGO · PI DRIKS, ADAM, HOEPRICH, PAUL DANIEL · 2011 to 2015
$3.3M
A systems level analysis of spore coat assembly in Bacillus subtilisR01GM081571 · NIGMS · NEW YORK UNIVERSITY · PI EICHENBERGER, PATRICK · 2008 to 2012
$1.5M
Localization and characterization of the Clostridium difficile biofilmR21AI097934 · NIAID · LOYOLA UNIVERSITY CHICAGO · PI DRIKS, ADAM · 2012 to 2013
$411k
NIAID NIH HHS R01 AI093493NIAID NIH HHS R01AI093493NIAID NIH HHS R21 AI097934NIAID NIH HHS R21AI097934NIGMS NIH HHS GM081571NIGMS NIH HHS R01 GM081571
6 · The paper itself

Abstract

Sporulation in Bacillus subtilis involves an asymmetric cell division followed by differentiation into two cell types, the endospore and the mother cell. The endospore coat is a multilayered shell that protects the bacterial genome during stress conditions and is composed of dozens of proteins. Recently, fluorescence microscopy coupled with high-resolution image analysis has been applied to the dynamic process of coat assembly and has shown that the coat is organized into at least four distinct layers. In this Review, we provide a brief summary of B. subtilis sporulation, describe the function of the spore surface layers and discuss the recent progress that has improved our understanding of the structure of the endospore coat and the mechanisms of coat assembly.

Indexed as

Bacillus subtilisBacterial ProteinsCell DivisionImage Processing, Computer-AssistedMicroscopy, FluorescenceModels, BiologicalProtein MultimerizationSpores, BacterialBacterial Proteinsspore-specific proteins, Bacillus

Identifiers

PMID23202530
PMCPMC9910062
OpenAlexW2131426382

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.