Evidence map›Paper›PMID 23202239›Full record

ReviewSensors (Basel, Switzerland)2012

Thiol reactive probes and chemosensors.

Hanjing Peng, Weixuan Chen, Yunfeng Cheng, Lovemore Hakuna, Robert Strongin, Binghe Wang

Open access · goldAbstract readReview
In one paragraph

Review in Sensors (Basel, Switzerland), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
17.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 272 citations in OpenAlex.

  1. Article
  2. Advancing QuantitativeACS macro letters · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Construction of a mitochondria-targeted probe to monitor cysteine levels in cancer cells and zebrafish.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2024
    Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Masked Amino Trimethyl Lock (HChemistry (Weinheim an der Bergstrasse, Germany) · 2022
    Article
  16. Review
  17. Article
  18. Article
  19. A modular template for the design of thiol-triggered sensors and prodrugs.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Hanjing PengDepartment of Chemistry, Center for Biotechnology and Drug Design, Georgia State University, Atlanta, GA 30302, USA. hpeng2@gsu.edu
Weixuan Chen
Yunfeng Cheng
Lovemore Hakuna
Robert Strongin
Binghe Wang
Georgia State University · USPortland State University · US

Funding

Selection of Boronic Acid-modified Aptamers for GlycoproteinsR01GM084933 · NIGMS · GEORGIA STATE UNIVERSITY · PI WANG, BINGHE · 2008 to 2011
$1.2M
NIGMS NIH HHS GM084933NIGMS NIH HHS R01 GM084933
6 · The paper itself

Abstract

Thiols are important molecules in the environment and in biological processes. Cysteine (Cys), homocysteine (Hcy), glutathione (GSH) and hydrogen sulfide (H(2)S) play critical roles in a variety of physiological and pathological processes. The selective detection of thiols using reaction-based probes and sensors is very important in basic research and in disease diagnosis. This review focuses on the design of fluorescent and colorimetric probes and sensors for thiol detection. Thiol detection methods include probes and labeling agents based on nucleophilic addition and substitution, Michael addition, disulfide bond or Se-N bond cleavage, metal-sulfur interactions and more. Probes for H(2)S are based on nucleophilic cyclization, reduction and metal sulfide formation. Thiol probe and chemosensor design strategies and mechanism of action are discussed in this review.

Indexed as

AnimalsBiosensing TechniquesFluorescent DyesHeLa CellsHumansLimit of DetectionMiceSulfhydryl CompoundsFluorescent DyesSulfhydryl Compounds

Identifiers

PMID23202239
PMCPMC3522992
OpenAlexW1967094458

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.