ReviewSensors (Basel, Switzerland)2012
Porous bead-based diagnostic platforms: bridging the gaps in healthcare.
Review in Sensors (Basel, Switzerland), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Engineering Innovative Interfaces for Point-of-Care Diagnostics.Current opinion in colloid & interface science · 2023Review
- Uncovering the Depths of the Human Proteome: Antibody-based Technologies for Ultrasensitive Multiplexed Protein Detection and Quantification.Molecular & cellular proteomics : MCP · 2021Review
- Review
- Trends of Bead Counting-Based Technologies Toward the Detection of Disease-Related Biomarkers.Frontiers in chemistry · 2020Review
- Sensors that Learn: The Evolution from Taste Fingerprints to Patterns of Early Disease Detection.Micromachines · 2019Review
- Fabrication of Artificial Leaf to Develop Fluid Pump Driven by Surface Tension and Evaporation.Scientific reports · 2017Article
- Simultaneous capture and sequential detection of two malarial biomarkers on magnetic microparticles.Talanta · 2016Article
- Programmable Bio-nanochip Platform: A Point-of-Care Biosensor System with the Capacity To Learn.Accounts of chemical research · 2016Article
- Cardiac ScoreCard: A Diagnostic Multivariate Index Assay System for Predicting a Spectrum of Cardiovascular Disease.Expert systems with applications · 2016Article
- Controlled Bulk Properties of Composite Polymeric Solutions for Extensive Structural Order of Honeycomb Polysulfone Membranes.Membranes · 2016Article
- Challenges and opportunities for translating medical microdevices: insights from the programmable bio-nano-chip.Bioanalysis · 2016Article
- Development of a Microsphere-Based System to Facilitate Real-Time Insulin Monitoring.Journal of diabetes science and technology · 2016Article
- Programmable bio-nano-chip system: a flexible point-of-care platform for bioscience and clinical measurements.Lab on a chip · 2015Article
- Programmable bio-nano-chip system: a flexible diagnostic platform that learns.Journal of biosensors & bioelectronics · 2015Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Advances in lab-on-a-chip systems have strong potential for multiplexed detection of a wide range of analytes with reduced sample and reagent volume; lower costs and shorter analysis times. The completion of high-fidelity multiplexed and multiclass assays remains a challenge for the medical microdevice field; as it struggles to achieve and expand upon at the point-of-care the quality of results that are achieved now routinely in remote laboratory settings. This review article serves to explore for the first time the key intersection of multiplexed bead-based detection systems with integrated microfluidic structures alongside porous capture elements together with biomarker validation studies. These strategically important elements are evaluated here in the context of platform generation as suitable for near-patient testing. Essential issues related to the scalability of these modular sensor ensembles are explored as are attempts to move such multiplexed and multiclass platforms into large-scale clinical trials. Recent efforts in these bead sensors have shown advantages over planar microarrays in terms of their capacity to generate multiplexed test results with shorter analysis times. Through high surface-to-volume ratios and encoding capabilities; porous bead-based ensembles; when combined with microfluidic elements; allow for high-throughput testing for enzymatic assays; general chemistries; protein; antibody and oligonucleotide applications.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.