SynthesisThe Journal of infection2013
The incubation period of cholera: a systematic review.
Synthesis in The Journal of infection, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 2 of them syntheses that pooled it.
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Who cites it
76 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Determinants of cholera among affected population of Ethiopia: a systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Times to key events in Zika virus infection and implications for blood donation: a systematic review.Bulletin of the World Health Organization · 2016Pooled it
- MODELING AND SIMULATING CHOLERA TRANSMISSION DYNAMICS WITH EVOLUTIONARY GAME THEORY.Numerical algebra, control and optimization · 2026Article
- Two decades of cholera in Dhaka, Bangladesh: Epidemiology, seasonal patterns, and environmental risk, insights from 2004-2024.PLoS neglected tropical diseases · 2026Article
- Quantifying the population-level impact of expanded antibiotic treatment for cholera outbreak management.PLoS computational biology · 2026Article
- Estimating the impact of decreasing vaccination response times for outbreaks of vaccine-preventable diseases in low- and middle-income countries.BMC global and public health · 2026Article
- Detection of toxigenicIDCases · 2026Article
- Determinants of Cholera in Selected Districts of Southeastern Part of Oromia Region, Ethiopia: A Case-Control Study.Environmental health insights · 2026Article
- The management of cholera in populations affected by conflict in Africa and the Middle-East: a scoping review.Conflict and health · 2025Review
- Cholera outbreak associated with drinking contaminated lake shore water, Namayingo District, Uganda, July-August 2023.BMC public health · 2025Article
- Cholera outbreak associated with drinking contaminated river water in Kayunga District, Uganda, June - August 2023.BMC infectious diseases · 2025Article
- Spatio-temporal pattern and risk factors associated with cholera outbreaks in selected high-risk areas of Kenya.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2025Article
- A Theoretical Framework to Quantify the Tradeoff Between Individual and Population Benefits of Expanded Antibiotic Use.Bulletin of mathematical biology · 2025Article
- Epidemiological investigation of a cholera outbreak in Nepal-India border communities: Public health implications.IJID regions · 2025Article
- Inferring the proportion of undetected cholera infections from serological and clinical surveillance in an immunologically naive population.Epidemiology and infection · 2024Article
- Impacts of climate change on diarrhoeal disease hospitalisations: How does the global warming targets of 1.5-2°C affect Dhaka, Bangladesh?PLoS neglected tropical diseases · 2024Article
- Article
- Case-area targeted interventions during a large-scale cholera epidemic: A prospective cohort study in Northeast Nigeria.PLoS medicine · 2024Observational
- Cholera rages in Africa and the Middle East: A narrative review on challenges and solutions.Health science reports · 2024Review
- Water pollution, cholera, and the role of probiotics: a comprehensive review in relation to public health in Bangladesh.Frontiers in microbiology · 2024Review
16 more citing papers are in PubMed but not listed here.
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4 authors.
Funding
Abstract
objectivesRecent large cholera outbreaks highlight the need for improved understanding of the pathogenesis and epidemiology of cholera. The incubation period of cholera has important implications for clinical and public health decision-making, yet statements of the incubation period of cholera are often imprecise. Here we characterize the distribution of cholera's incubation period.
methodsWe conducted a systematic review of the literature for statements of the incubation period of cholera and data that might aid in its estimation. We extracted individual-level data, parametrically estimated the distribution of toxigenic cholera's incubation period, and evaluated evidence for differences between strains.
resultsThe incubation period did not differ by a clinically significant margin between strains (except O1 El Tor Ogawa). We estimate the median incubation period of toxigenic cholera to be 1.4 days (95% CI, 1.3-1.6). Five percent of cholera cases will develop symptoms by 0.5 days (95% CI 0.4-0.5), and 95% by 4.4 days (95% CI 3.9-5.0) after infection.
conclusionsWe recommend that cholera investigations use a recall period of at least five days to capture relevant exposures; significantly longer than recent risk factor studies from the Haitian epidemic. This characterization of cholera's incubation period can help improve clinical and public health practice and advance epidemiologic research.
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