Evidence map›Paper›PMID 23201850›Full record

ReviewInfection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases2013

Inter and intra-specific diversity of parasites that cause lymphatic filariasis.

Samantha N McNulty, Makedonka Mitreva, Gary J Weil, Peter U Fischer

Open access · hybridAbstract readReview
In one paragraph

Review in Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Redescription, molecular characterisation andCurrent research in parasitology & vector-borne diseases · 2024
    Article
  6. Host genetic backgrounds: the key to determining parasite-host adaptation.Frontiers in cellular and infection microbiology · 2023
    Review
  7. Article
  8. Article
  9. Article
  10. Molecular Characterization of a ReemergentBioMed research international · 2021
    Article
  11. New Molecular Data on Filaria and itsPathogens (Basel, Switzerland) · 2020
    Article
  12. DNA ofVeterinary world · 2020
    Article
  13. Review
  14. Review
  15. Viruses · 2019
    Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Molecular epidemiology, phylogeny and evolution of the filarial nematode Wuchereria bancrofti.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Samantha N McNultyInfectious Diseases Division, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, United States.
Makedonka Mitreva
Gary J Weil
Peter U Fischer
Washington University in St. Louis · US

Funding

COMPARATIVE GENOMICS OF PARASITIC NEMATODESR01AI081803 · NIAID · WASHINGTON UNIVERSITY · PI MITREVA, MAKEDONKA · 2009 to 2018
$3.1M
NIAID NIH HHS R01 AI081803
6 · The paper itself

Abstract

Lymphatic filariasis is caused by three closely related nematode parasites: Wuchereria bancrofti, Brugia malayi and Brugia timori. These species have many ecological variants that differ in several aspects of their biology such as mosquito vector species, host range, periodicity, and morphology. Although the genome of B. malayi (the first genome sequenced from a parasitic nematode) has been available for more than five years, very little is known about genetic variability among the lymphatic dwelling filariae. The genetic diversity among these worms is not only interesting from a biological perspective, but it may have important practical implications for the Global Program to Eliminate Lymphatic Filariasis, as the parasites may respond differently to diagnostic tests and/or medical interventions. Therefore, better information on their genetic variability is urgently needed. With improved methods for nucleic acid extraction and recent advances in sequencing chemistry and instrumentation, this gap can be filled relatively inexpensively. Improved information on filarial genetic diversity may increase the chances of success for lymphatic filariasis elimination programs.

Indexed as

BiodiversityNeglected DiseasesAnimalsAnthelminticsBrugiaElephantiasis, FilarialGenetic VariationGenome, ProtozoanSelection, GeneticWuchereria bancroftiAnthelmintics

Identifiers

PMID23201850
PMCPMC3801268
OpenAlexW2157955681

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.