ReviewNutrients2012
Risk of parenteral nutrition in neonates--an overview.
Review in Nutrients, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 57 citations in OpenAlex.
- Trial
- The Prevalence and Impact of Bacteremia Among Neonates Receiving Parenteral Nutrition: A Multicenter Retrospective Study from Saudi Arabia.Pharmacy (Basel, Switzerland) · 2026Article
- Bovine colostrum as a human milk fortifier for very preterm infants with slow feeding advancement: a randomized controlled trial.Pediatric research · 2026Article
- Rapid assessment of feeding intolerance: a systematic approach to reduce time to full enteral feeding in preterm infants.Frontiers in pediatrics · 2026Article
- Article
- Efficacy and Safety of Orogastric vs. Nasogastric Tube Feeding in Preterm Infants: A Systematic Review and Meta-Analysis.Children (Basel, Switzerland) · 2024Review
- Invasive Candida Infections in Neonatal Intensive Care Units: Risk Factors and New Insights in Prevention.Pathogens (Basel, Switzerland) · 2024Review
- Antisecretory factor in breastmilk is associated with reduced incidence of sepsis in preterm infants.Pediatric research · 2024Article
- Exposure of preterm neonates receiving total parenteral nutrition to phthalates and its impact on neurodevelopment at the age of 2 months.Scientific reports · 2023Article
- An Observational Study on the Use of Peripheral Intravenous Lines vs. Central Lines in a Neonatal Intensive Care Unit.Children (Basel, Switzerland) · 2022Article
- Catheter-related bloodstream infections in infants hospitalized in neonatal intensive care units: a single center study.Scientific reports · 2022Article
- Use of parenteral nutrition in the first postnatal week in England and Wales: an observational study using real-world data.BMJ paediatrics open · 2022Observational
- Metabolic-endocrine disruption due to preterm birth impacts growth, body composition, and neonatal outcome.Pediatric research · 2022Review
- Fluid Supply and Feeding Practices in Cooled Asphyxiated Newborns.Children (Basel, Switzerland) · 2021Article
- Article
- Outcomes and survival of infants with congenital duodenal obstruction following Kimura procedure with post-anastomosis jejunostomy feeding tube.BMC gastroenterology · 2021Article
- Parenteral Nutrition Process Management for Newborn and Preterm Infants - A Preliminary Risk Analysis.Therapeutics and clinical risk management · 2021Article
- Quality and safety of parenteral nutrition for newborn and preterm infants as an on-ward preparation.European journal of hospital pharmacy : science and practice · 2020Article
- The related factors of phlebitis among low birth weight infants in perinatology ward.Pediatric reports · 2020Article
- Adequacy of Parenteral Nutrition in Preterm Infants According to Current Recommendations: A Study in A Spanish Hospital.International journal of environmental research and public health · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Healthcare-associated infections (HAI) in preterm infants are a challenge to the care of these fragile patients. HAI-incidence rates range from 6 to 27 infections per 1000 patient-days. Most nosocomial infections are bloodstream infections and of these, the majority is associated with the use of central venous catheters. Many studies identified parenteral nutrition as an independent risk factor for HAI, catheter-associated bloodstream infection, and clinical sepsis. This fact and various published outbreaks due to contaminated parenteral nutrition preparations highlight the importance of appropriate standards in the preparation and handling of intravenous solutions and parenteral nutrition. Ready-to-use parenteral nutrition formulations may provide additional safety in this context. However, there is concern that such formulations may result in overfeeding and necrotizing enterocolitis. Given the risk for catheter-associated infection, handling with parenteral nutrition should be minimized and the duration shortened. Further research is required about this topic.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.