ReviewInternational journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience2013
Gestational overgrowth and undergrowth affect neurodevelopment: similarities and differences from behavior to epigenetics.
Review in International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 1 synthesis or guideline pooled it, 130 citations in OpenAlex.
- Effects of high-fat diets on fetal growth in rodents: a systematic review.Reproductive biology and endocrinology : RB&E · 2019Pooled it
- Trial
- Long-term neurodevelopmental outcomes after vacuum-assisted delivery: A population-based cohort study.PLoS medicine · 2026Article
- Article
- Translational implications of circadian activity alterations in an experimental model of late-onset depression induced by prenatal excess of glucocorticoids.Frontiers in behavioral neuroscience · 2025Review
- Maternal high-fat or low-protein diets promote autism-related behavior and altered social behavior within groups in offspring male mice.Scientific reports · 2024Article
- Article
- Postnatal Growth and Prevalence of Obesity in Infants Born Large-for-Gestational Age during the First 3 years of Life: Personal Experience and Exploration of Current Literature.Acta bio-medica : Atenei Parmensis · 2022Article
- Morbidity and psychomotor development of offspring of women with gestational diabetes: a 5-year follow-up.BMC pediatrics · 2022Article
- Association between birth weight and neurodevelopmental disorders assessed using the Korean National Health Insurance Service claims data.Scientific reports · 2022Article
- Grain consumption before and during pregnancy and birth weight in Japan: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study.European journal of clinical nutrition · 2022Article
- Lower hypothalamus subunit volumes link with impaired long-term body weight gain after preterm birth.Frontiers in endocrinology · 2022Article
- Placental endocrine insufficiency programs anxiety, deficits in cognition and atypical social behaviour in offspring.Human molecular genetics · 2021Article
- Proximal variants in CCND2 associated with microcephaly, short stature, and developmental delay: A case series and review of inverse brain growth phenotypes.American journal of medical genetics. Part A · 2021Review
- Protein Appetite Drives Macronutrient-Related Differences in Ventral Tegmental Area Neural Activity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Antenatal depressive symptoms and adverse perinatal outcomes.BMC pregnancy and childbirth · 2021Article
- Age-dependent effects of protein restriction on dopamine release.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021Article
- Article
- Impact of Early Nutrition, Physical Activity and Sleep on the Fetal Programming of Disease in the Pregnancy: A Narrative Review.Nutrients · 2020Review
- Associations between maternal dietary patterns and infant birth weight, small and large for gestational age in the Norwegian Mother and Child Cohort Study.European journal of clinical nutrition · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The size of an infant at birth, a measure of gestational growth, has been recognized for many years as a biomarker of future risk of morbidity. Both being born small for gestational age (SGA) and being born large for gestational age (LGA), are associated with increased rates of obesity and metabolic disorder, as well as a number of mental disorders including attention deficit/hyperactivity disorder, autism, anxiety, and depression. The common risks raise the question of what neurobiological mechanisms are altered in SGA and LGA offspring. Here we review recent findings allowing for direct comparison of neurobiological outcomes of SGA and LGA in human and animal models. We also present new data highlighting similarities and differences in behavior and neurobiology in our mouse models of SGA and LGA. Overall, there is significant data to support aberrant epigenetic mechanisms, particularly related to DNA methylation, in the brains of SGA and LGA offspring, leading to disruptions in the cell cycle in development and gene expression in adulthood.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.