Evidence map›Paper›PMID 23200904›Full record

ArticleJournal of biomechanics2013

Numerical and experimental investigation of pulsatile hemodynamics in the total cavopulmonary connection.

Elaine Tang, Christopher M Haggerty, Reza H Khiabani, Diane de Zélicourt, Jessica Kanter, Fotis Sotiropoulos, Mark A Fogel, Ajit P Yoganathan

Abstract read
In one paragraph

Article in Journal of biomechanics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elaine TangSchool of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA 30332, United States.
Christopher M Haggerty
Reza H Khiabani
Diane de Zélicourt
Jessica Kanter
Fotis Sotiropoulos
Mark A Fogel
Ajit P Yoganathan

Funding

Improving Flow Dynamics in Fontan SurgeriesR01HL067622 · NHLBI · GEORGIA INSTITUTE OF TECHNOLOGY · PI YOGANATHAN, AJIT P · 2002 to 2006
$5.2M
Understanding mechanisms of Fontan failure and key predictors for patient outcomeR01HL098252 · NHLBI · GEORGIA INSTITUTE OF TECHNOLOGY · PI YOGANATHAN, AJIT P · 2010 to 2013
$3.0M
NHLBI NIH HHS HL67622NHLBI NIH HHS R01 HL067622NHLBI NIH HHS R01 HL098252NHLBI NIH HHS R01HL098252
6 · The paper itself

Abstract

Computational fluid dynamics (CFD) tools have been extensively applied to study the hemodynamics in the total cavopulmonary connection (TCPC) in patients with only a single functioning ventricle. Without the contraction of a sub-pulmonary ventricle, pulsatility of flow through this connection is low and variable across patients, which is usually neglected in most numerical modeling studies. Recent studies suggest that such pulsatility can be non-negligible and can be important in hemodynamic predictions. The goal of this work is to compare the results of an in-house numerical methodology for simulating pulsatile TCPC flow with experimental results. Digital particle image velocimetry (DPIV) was acquired on TCPC in vitro models to evaluate the capability of the CFD tool in predicting pulsatile TCPC flow fields. In vitro hemodynamic measurements were used to compare the numerical prediction of power loss across the connection. The results demonstrated the complexity of the pulsatile TCPC flow fields and the validity of the numerical approach in simulating pulsatile TCPC flow dynamics in both idealized and complex patient specific models.

Indexed as

Computer SimulationModels, CardiovascularPulsatile FlowHeart VentriclesHumans

Identifiers

PMID23200904
PMCPMC3552075

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.