ReviewLancet (London, England)2012
Ecology of zoonoses: natural and unnatural histories.
Review in Lancet (London, England), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 426 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
426 citing papers in PubMed, 5 syntheses or guidelines pooled it, 885 citations in OpenAlex.
- Systematic Review and Meta-Analysis of Emerging Viral Zoonotic Diseases, 2016-2026.Transboundary and emerging diseases · 2026Pooled it
- Change in Formal and Informal Forest Management Institutions Induced by Health Shocks-A Global Systematic Review.Environmental management · 2025Pooled it
- Zoonotic pathogens in equids in Central Europe: a systematic review.BMC veterinary research · 2025Pooled it
- Zoos as Sentinels? A Meta-Analysis of Seroprevalence of Terrestrial Mammalian Viruses in Zoos.EcoHealth · 2023Pooled it
- Evidence gaps and diversity among potential win-win solutions for conservation and human infectious disease control.The Lancet. Planetary health · 2022Pooled it
- Viral pathogens in urban rats: A one health systematic review of global surveillance evidence.One health (Amsterdam, Netherlands) · 2026Review
- School-based one health education shapes young minds and households to prevent zoonoses: A comparison of four teaching strategies.One health (Amsterdam, Netherlands) · 2026Article
- Spatio-temporal dynamics of Rift Valley fever virus circulation in sentinel livestock herds (2021-2024) before the initial fatal human outbreaks in Senegal.New microbes and new infections · 2026Article
- Spatio-Temporal Dynamics of Crimean Congo Hemorrhagic Fever Virus Infection Using Animal Sentinel Herds in Senegal: March 2021-June 2024.GeoHealth · 2026Article
- Qualitative Assessment of One Health Operationalization at the Central Level and in Two Border Districts of Sierra Leone.Public health challenges · 2026Article
- Eco-Bio-Communitarianism and Its Application to Clinical Research, Global Health, Biotechnology, and Environmental Protection.Journal of bioethical inquiry · 2026Article
- Shaping the Future Plate: Exploring the Safety Concerns of Cultivated and Conventional Meat Production.Physiological research · 2026Review
- How illegal wildlife trade adheres to and defies conventional market behavior.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Exploring community awareness and perspectives on zoonotic disease in Nepal: a qualitative study.BMC public health · 2026Article
- Understanding zoonotic spillover interfaces for the design of a One Health education intervention: a qualitative baseline study from rural Thailand.One health outlook · 2026Article
- Review
- Improved Detection and Sequencing of Rickettsia spp. DNA in South African Wildlife.Veterinary medicine and science · 2026Article
- Emerging Viral Zoonoses: Epidemiology, Vaccination Strategies, and Implications for Global Public Health.Vaccines · 2026Review
- Occurrence of third-generation cephalosporin-resistant Escherichia coli in European hedgehogs (Erinaceus europaeus) from a wildlife rescue centre in Lombardy, Northern Italy.Veterinary research communications · 2026Article
- Contrasting geographic patterns of parasite and hantavirus diversity in the rodent Oligoryzomys longicaudatus (Rodentia, Cricetidae).PLoS neglected tropical diseases · 2026Article
366 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 8 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
More than 60% of human infectious diseases are caused by pathogens shared with wild or domestic animals. Zoonotic disease organisms include those that are endemic in human populations or enzootic in animal populations with frequent cross-species transmission to people. Some of these diseases have only emerged recently. Together, these organisms are responsible for a substantial burden of disease, with endemic and enzootic zoonoses causing about a billion cases of illness in people and millions of deaths every year. Emerging zoonoses are a growing threat to global health and have caused hundreds of billions of US dollars of economic damage in the past 20 years. We aimed to review how zoonotic diseases result from natural pathogen ecology, and how other circumstances, such as animal production, extraction of natural resources, and antimicrobial application change the dynamics of disease exposure to human beings. In view of present anthropogenic trends, a more effective approach to zoonotic disease prevention and control will require a broad view of medicine that emphasises evidence-based decision making and integrates ecological and evolutionary principles of animal, human, and environmental factors. This broad view is essential for the successful development of policies and practices that reduce probability of future zoonotic emergence, targeted surveillance and strategic prevention, and engagement of partners outside the medical community to help improve health outcomes and reduce disease threats.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.